|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$250M
|
-$3.86M
|
-46,051
|
-1%
|
|
|
2
|
Janus Henderson Group
London,
|
$201M
|
+$74M
|
+882,440
|
+45%
|
|
|
3
|
Frazier Management
Seattle,
Washington
|
$165M
|
-$115M
|
-1,372,001
|
-37%
|
|
|
4
|
Adage Capital Partners
Boston,
Massachusetts
|
$110M
|
+$14.4M
|
+171,744
|
+12%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$110M
|
+$24.2M
|
+288,792
|
+23%
|
|
|
6
|
|
$104M
|
+$3.48M
|
+41,507
|
+3%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$92.5M
|
+$28.8M
|
+343,771
|
+36%
|
|
|
8
|
Cormorant Asset Management
Boston,
Massachusetts
|
$87.6M
|
+$10.9M
|
+129,400
|
+12%
|
|
|
9
|
OppenheimerFunds
New York
|
$78.3M
|
+$4.59M
|
+54,773
|
+5%
|
|
|
10
|
Citadel Advisors
Miami,
Florida
|
$59.1M
|
+$44.6M
|
+531,331
|
+177%
|
|
|
11
|
Deerfield Management
New York
|
$40M
|
-$19.4M
|
-231,349
|
-29%
|
|
|
12
|
Viking Global Investors
Stamford,
Connecticut
|
$38.6M
|
+$7.04M
|
+83,866
|
+18%
|
|
|
13
|
Redmile Group
San Francisco,
California
|
$36.9M
|
-$327K
|
-3,900
|
-0.7%
|
|
|
14
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$34.9M
|
+$4.21M
|
+50,170
|
+11%
|
|
|
15
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$30.9M
|
+$19.6M
|
+233,748
|
+116%
|
|
|
16
|
Capital World Investors
Los Angeles,
California
|
$27.5M
|
+$6.96M
|
+83,000
|
+27%
|
|
|
17
|
BVF Inc
San Francisco,
California
|
$23.8M
|
-$4.26M
|
-50,800
|
-13%
|
|
|
18
|
Millennium Management
New York
|
$16.7M
|
-$6.22M
|
-74,188
|
-24%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$15M
|
+$1.11M
|
+13,180
|
+7%
|
|
|
20
|
|
$14.2M
|
+$839K
|
+10,000
|
+5%
|
|
|
21
|
|
$11.8M
|
+$10.5M
|
+124,718
|
+306%
|
|
|
22
|
Two Sigma Investments
New York
|
$11.7M
|
+$13.6M
|
+162,157
|
+6,486%
|
|
|
23
|
Geode Capital Management
Boston,
Massachusetts
|
$11.5M
|
+$1M
|
+11,931
|
+8%
|
|
|
24
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$10.7M
|
+$1.26M
|
+15,000
|
+11%
|
|
|
25
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$10.5M
|
-$3.63M
|
-43,247
|
-23%
|
|
