|
1
|
EcoR1 Capital
San Francisco,
California
|
$204M
|
–
|
–
|
–
|
|
|
2
|
Tang Capital Management
San Diego,
California
|
$71.3M
|
–
|
–
|
–
|
|
|
3
|
|
$50.7M
|
+$489K
|
+19,273
|
+1%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$49.6M
|
-$1.39M
|
-54,911
|
-3%
|
|
|
5
|
Boxer Capital
San Diego,
California
|
$35.3M
|
–
|
–
|
–
|
|
|
6
|
Woodline Partners
San Francisco,
California
|
$27.5M
|
+$12M
|
+473,904
|
+88%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$26.2M
|
-$8M
|
-315,243
|
-25%
|
|
|
8
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$25.6M
|
+$987K
|
+38,866
|
+4%
|
|
|
9
|
Frazier Management
Seattle,
Washington
|
$24.4M
|
–
|
–
|
–
|
|
|
10
|
Dimensional Fund Advisors
Austin,
Texas
|
$20.5M
|
-$422K
|
-16,625
|
-2%
|
|
|
11
|
Great Point Partners
Greenwich,
Connecticut
|
$14.9M
|
+$3.79M
|
+149,494
|
+37%
|
|
|
12
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$14.5M
|
+$15.2K
|
+600
|
+0.1%
|
|
|
13
|
Palo Alto Investors
Palo Alto,
California
|
$11.8M
|
–
|
–
|
–
|
|
|
14
|
Baker Bros. Advisors
New York
|
$11.6M
|
–
|
–
|
–
|
|
|
15
|
Nuveen
Charlotte,
North Carolina
|
$11.4M
|
+$320K
|
+12,593
|
+3%
|
|
|
16
|
Cormorant Asset Management
Boston,
Massachusetts
|
$10.4M
|
–
|
–
|
–
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$9.73M
|
-$640K
|
-25,210
|
-7%
|
|
|
18
|
|
$9.43M
|
+$834K
|
+32,863
|
+10%
|
|
|
19
|
BVF Inc
San Francisco,
California
|
$9.07M
|
-$12M
|
-474,312
|
-59%
|
|
|
20
|
|
$8.91M
|
+$8.34M
|
+328,720
|
New
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$7.81M
|
-$285K
|
-11,214
|
-4%
|
|
|
22
|
|
$6.88M
|
-$123K
|
-4,852
|
-2%
|
|
|
23
|
|
$6.65M
|
-$1.56M
|
-61,391
|
-20%
|
|
|
24
|
Acadian Asset Management
Boston,
Massachusetts
|
$4.79M
|
+$388K
|
+15,270
|
+9%
|
|
|
25
|
Two Sigma Advisers
New York
|
$4.61M
|
-$2.52M
|
-99,100
|
-37%
|
|
