BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+4.49%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$9.36B
AUM Growth
+$9.36B
Cap. Flow
+$5.03M
Cap. Flow %
0.05%
Top 10 Hldgs %
76.51%
Holding
102
New
8
Increased
20
Reduced
5
Closed
7

Top Buys

1
INSM icon
Insmed
INSM
$40.8M
2
GRAL
GRAIL, Inc. Common Stock
GRAL
$29.1M
3
CADL icon
Candel Therapeutics
CADL
$25.9M
4
BCYC
Bicycle Therapeutics
BCYC
$20.8M
5
CRSP icon
CRISPR Therapeutics
CRSP
$18.3M

Top Sells

1
ONC
BeOne Medicines Ltd. American Depositary Shares
ONC
$192M
2
RYTM icon
Rhythm Pharmaceuticals
RYTM
$17.6M
3
TNGX icon
Tango Therapeutics
TNGX
$5.78M
4
CRNX icon
Crinetics Pharmaceuticals
CRNX
$5.31M
5
ALEC icon
Alector
ALEC
$4.32M

Sector Composition

1 Healthcare 98.69%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
ALGS icon
76
Aligos Therapeutics
ALGS
$75.1M
$3.31M 0.04%
83,055
– –
PRME icon
77
Prime Medicine
PRME
$595M
$3M 0.03%
1,028,466
– –
TARA icon
78
Protara Therapeutics
TARA
$125M
$2.83M 0.03%
536,832
– –
ELVN icon
79
Enliven Therapeutics
ELVN
$1.24B
$2.58M 0.03%
114,833
– –
ARCT icon
80
Arcturus Therapeutics
ARCT
$467M
$2.57M 0.03%
151,329
– –
CMPX icon
81
Compass Therapeutics
CMPX
$466M
$2.26M 0.02%
1,557,630
– –
GBIO icon
82
Generation Bio
GBIO
$40.3M
$2.06M 0.02%
1,944,945
– –
HOOK
83
DELISTED
HOOKIPA Pharma
HOOK
$1.63M 0.02%
812,814
– –
MRSN icon
84
Mersana Therapeutics
MRSN
$34.8M
$1.55M 0.02%
1,086,115
– –
VTVT icon
85
vTv Therapeutics
VTVT
$49.4M
$1.34M 0.01%
97,314
– –
RCKT icon
86
Rocket Pharmaceuticals
RCKT
$358M
$1.22M 0.01%
+97,079
New +$1.22M
PTCT icon
87
PTC Therapeutics
PTCT
$4.41B
$921K 0.01%
+20,400
New +$921K
IPSC icon
88
Century Therapeutics
IPSC
$40.4M
$805K 0.01%
797,460
– –
PMVP icon
89
PMV Pharmaceuticals
PMVP
$82.1M
$486K 0.01%
322,024
– –
ACRV icon
90
Acrivon Therapeutics
ACRV
$42.2M
$318K ﹤0.01%
52,885
– –
FHTX icon
91
Foghorn Therapeutics
FHTX
$298M
$213K ﹤0.01%
45,027
– –
TYRA icon
92
Tyra Biosciences
TYRA
$657M
$147K ﹤0.01%
10,607
– –
SRZNW icon
93
Surrozen, Inc. Warrant
SRZNW
$71.9K
$17.8K ﹤0.01%
833,333
– –
TNGX icon
94
Tango Therapeutics
TNGX
$745M
– –
-750,000
Closed -$5.78M
PFE icon
95
Pfizer
PFE
$141B
– –
-35,000
Closed -$1.01M
NAMS icon
96
NewAmsterdam Pharma
NAMS
$2.8B
– –
-96,711
Closed -$1.61M
CRNX icon
97
Crinetics Pharmaceuticals
CRNX
$3.26B
– –
-103,927
Closed -$5.31M
BCRX icon
98
BioCryst Pharmaceuticals
BCRX
$1.74B
– –
-75,778
Closed -$576K
JBIO
99
Jade Biosciences, Inc. Common Stock
JBIO
$245M
– –
-628,939
Closed -$1.31M
ALEC icon
100
Alector
ALEC
$282M
– –
-927,264
Closed -$4.32M
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