BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
-1.31%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$15.3B
AUM Growth
+$15.3B
Cap. Flow
-$285M
Cap. Flow %
-1.86%
Top 10 Hldgs %
84.69%
Holding
129
New
12
Increased
7
Reduced
17
Closed
13

Top Buys

1
AKRO icon
Akero Therapeutics
AKRO
$76.6M
2
RYTM icon
Rhythm Pharmaceuticals
RYTM
$47.5M
3
CINC
CinCor Pharma, Inc. Common Stock
CINC
$26.5M
4
IDYA icon
IDEAYA Biosciences
IDYA
$24.9M
5
BCYC
Bicycle Therapeutics
BCYC
$19.6M

Top Sells

1
ARGX icon
argenx
ARGX
$296M
2
LEGN icon
Legend Biotech
LEGN
$47.1M
3
INSM icon
Insmed
INSM
$46M
4
KRYS icon
Krystal Biotech
KRYS
$26.9M
5
PACB icon
Pacific Biosciences
PACB
$25.1M

Sector Composition

1 Healthcare 98.97%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
KRON
76
DELISTED
Kronos Bio
KRON
$5.16M 0.03%
+1,539,616
New +$5.16M
CYT
77
DELISTED
Cyteir Therapeutics, Inc. Common Stock
CYT
$5.08M 0.03%
2,643,640
– –
SRZN icon
78
Surrozen
SRZN
$107M
$5.05M 0.03%
2,500,000
– –
EWTX icon
79
Edgewise Therapeutics
EWTX
$1.54B
$4.92M 0.03%
500,000
– –
FATE icon
80
Fate Therapeutics
FATE
$115M
$4.83M 0.03%
+215,695
New +$4.83M
STOK icon
81
Stoke Therapeutics
STOK
$1.08B
$4.74M 0.03%
+369,327
New +$4.74M
RVMD icon
82
Revolution Medicines
RVMD
$7.43B
$4.38M 0.03%
222,222
– –
NTRA icon
83
Natera
NTRA
$23B
$4.38M 0.03%
100,000
– –
ALLK
84
DELISTED
Allakos
ALLK
$4.3M 0.03%
703,050
– –
EIGR
85
DELISTED
Eiger BioPharmaceuticals, Inc.
EIGR
$4.07M 0.03%
+539,851
New +$4.07M
PMVP icon
86
PMV Pharmaceuticals
PMVP
$82.1M
$3.83M 0.03%
+322,024
New +$3.83M
IPSC icon
87
Century Therapeutics
IPSC
$40.4M
$3.67M 0.02%
+370,587
New +$3.67M
HOOK
88
DELISTED
HOOKIPA Pharma
HOOK
$3.22M 0.02%
2,400,481
– –
ATHA icon
89
Athira Pharma
ATHA
$15.5M
$3.09M 0.02%
1,040,834
– –
MGNX icon
90
MacroGenics
MGNX
$121M
$3.09M 0.02%
892,579
– –
ITOS
91
DELISTED
iTeos Therapeutics
ITOS
$2.86M 0.02%
150,346
– –
ATRA icon
92
Atara Biotherapeutics
ATRA
$88.7M
$2.81M 0.02%
744,186
– –
TNGX icon
93
Tango Therapeutics
TNGX
$745M
$2.72M 0.02%
750,000
– –
SNDX icon
94
Syndax Pharmaceuticals
SNDX
$1.39B
$2.66M 0.02%
110,729
– –
OTIC
95
DELISTED
Otonomy, Inc.
OTIC
$2.49M 0.02%
8,443,134
+30,500
+0.4% +$9K
NGNE icon
96
Neurogene
NGNE
$284M
$2.45M 0.02%
3,821,740
– –
ALGS icon
97
Aligos Therapeutics
ALGS
$75.1M
$2.28M 0.02%
2,076,400
– –
ALEC icon
98
Alector
ALEC
$282M
$2.26M 0.01%
239,228
– –
SYRE icon
99
Spyre Therapeutics
SYRE
$1.02B
$1.79M 0.01%
3,410,106
– –
TCRR
100
DELISTED
TCR2 Therapeutics Inc. Common Stock
TCRR
$1.36M 0.01%
753,064
– –
2 3
4
5 6