BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+6.18%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$17.6B
AUM Growth
+$17.6B
Cap. Flow
+$50.9M
Cap. Flow %
0.29%
Top 10 Hldgs %
87.48%
Holding
123
New
5
Increased
24
Reduced
7
Closed
6

Top Buys

1
REPL icon
Replimune Group
REPL
$34.6M
2
ASND icon
Ascendis Pharma
ASND
$28.9M
3
CCXI
ChemoCentryx, Inc.
CCXI
$21.7M
4
HZNP
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
$19.9M
5
NRIX icon
Nurix Therapeutics
NRIX
$18.1M

Top Sells

1
NBIX icon
Neurocrine Biosciences
NBIX
$63.5M
2
LEGN icon
Legend Biotech
LEGN
$63.4M
3
AXSM icon
Axsome Therapeutics
AXSM
$25.3M
4
MRUS icon
Merus
MRUS
$23.6M
5
SRPT icon
Sarepta Therapeutics
SRPT
$9.64M

Sector Composition

1 Healthcare 99.17%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
CNTA
76
Centessa Pharmaceuticals
CNTA
$2.13B
$5.49M 0.03%
1,127,273
– –
NKTX icon
77
Nkarta
NKTX
$149M
$4.93M 0.03%
+400,000
New +$4.93M
VERA icon
78
Vera Therapeutics
VERA
$1.47B
$4.54M 0.03%
333,333
– –
RVMD icon
79
Revolution Medicines
RVMD
$7.43B
$4.33M 0.02%
222,222
– –
EWTX icon
80
Edgewise Therapeutics
EWTX
$1.54B
$3.98M 0.02%
500,000
– –
NGNE icon
81
Neurogene
NGNE
$284M
$3.94M 0.02%
3,821,740
– –
HOOK
82
DELISTED
HOOKIPA Pharma
HOOK
$3.91M 0.02%
2,400,481
– –
NTRA icon
83
Natera
NTRA
$23B
$3.54M 0.02%
+100,000
New +$3.54M
TNGX icon
84
Tango Therapeutics
TNGX
$745M
$3.4M 0.02%
750,000
– –
ATHA icon
85
Athira Pharma
ATHA
$15.5M
$3.18M 0.02%
1,040,834
+234,467
+29% +$715K
ITOS
86
DELISTED
iTeos Therapeutics
ITOS
$3.1M 0.02%
150,346
– –
EVFM
87
DELISTED
Evofem Biosciences, Inc. Common Stock
EVFM
$2.92M 0.02%
+2,583,616
New +$2.92M
MGNX icon
88
MacroGenics
MGNX
$121M
$2.63M 0.01%
892,579
+450,000
+102% +$1.33M
ALGS icon
89
Aligos Therapeutics
ALGS
$75.1M
$2.51M 0.01%
2,076,400
– –
ALEC icon
90
Alector
ALEC
$282M
$2.43M 0.01%
239,228
– –
BCAB icon
91
BioAtla
BCAB
$28.7M
$2.35M 0.01%
825,000
– –
ALLK
92
DELISTED
Allakos
ALLK
$2.2M 0.01%
703,050
– –
TCRR
93
DELISTED
TCR2 Therapeutics Inc. Common Stock
TCRR
$2.18M 0.01%
753,064
– –
SNDX icon
94
Syndax Pharmaceuticals
SNDX
$1.39B
$2.13M 0.01%
110,729
– –
SYRE icon
95
Spyre Therapeutics
SYRE
$1.02B
$1.72M 0.01%
3,410,106
– –
EPZM
96
DELISTED
Epizyme, Inc
EPZM
$1.47M 0.01%
1,000,000
– –
AKRO icon
97
Akero Therapeutics
AKRO
$3.65B
$1.12M 0.01%
118,378
– –
ATYR
98
aTyr Pharma
ATYR
$560M
$1.06M 0.01%
374,395
-250,605
-40% -$710K
GTH
99
DELISTED
Genetron Holdings Limited ADS
GTH
$774K ﹤0.01%
455,306
– –
NGM
100
DELISTED
NGM Biopharmaceuticals, Inc. Common Stock
NGM
$709K ﹤0.01%
55,294
-236,507
-81% -$3.03M
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4
5