BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
-6.77%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$23.1B
AUM Growth
+$23.1B
Cap. Flow
-$142M
Cap. Flow %
-0.62%
Top 10 Hldgs %
80.48%
Holding
138
New
11
Increased
23
Reduced
15
Closed
12

Top Buys

1
IMCR icon
Immunocore
IMCR
$107M
2
TIL icon
Instil Bio
TIL
$97.7M
3
TLIS
Talis Biomedical Corporation Common Stock
TLIS
$97.3M
4
GBT
Global Blood Therapeutics, Inc.
GBT
$93.6M
5
DSGN icon
Design Therapeutics
DSGN
$43M

Top Sells

1
ALXN
Alexion Pharmaceuticals Inc
ALXN
$729M
2
ADPT icon
Adaptive Biotechnologies
ADPT
$22.5M
3
GWPH
GW Pharmaceuticals Plc American Depositary Shares
GWPH
$13M
4
FPRX
Five Prime Therapeutics, Inc.
FPRX
$11.4M
5
AMRN
Amarin Corp
AMRN
$9.55M

Sector Composition

1 Healthcare 97.06%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
ANAB icon
76
AnaptysBio
ANAB
$594M
$9.21M 0.04%
427,179
– –
ISEE
77
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$8.69M 0.04%
1,406,037
– –
NGM
78
DELISTED
NGM Biopharmaceuticals, Inc. Common Stock
NGM
$8.48M 0.04%
291,801
+185,185
+174% +$5.38M
KRTX
79
DELISTED
Karuna Therapeutics, Inc. Common Stock
KRTX
$8.41M 0.04%
69,966
– –
GMDA
80
DELISTED
Gamida Cell Ltd. Ordinary Shares
GMDA
$8.39M 0.04%
1,037,226
-511,088
-33% -$4.13M
ASMB icon
81
Assembly Biosciences
ASMB
$184M
$7.09M 0.03%
1,541,418
– –
CABA icon
82
Cabaletta Bio
CABA
$138M
$7.06M 0.03%
636,363
– –
BLUE
83
DELISTED
bluebird bio
BLUE
$6.84M 0.03%
226,988
– –
MGNX icon
84
MacroGenics
MGNX
$121M
$6.39M 0.03%
200,679
– –
BNR
85
Burning Rock Biotech
BNR
$86.9M
$5.63M 0.02%
209,131
– –
NEXI
86
DELISTED
NexImmune, Inc. Common Stock
NEXI
$5.61M 0.02%
+294,117
New +$5.61M
SGMO icon
87
Sangamo Therapeutics
SGMO
$165M
$5.38M 0.02%
429,063
-428,276
-50% -$5.37M
ORTX
88
DELISTED
Orchard Therapeutics plc American Depositary Shares
ORTX
$5.33M 0.02%
734,431
+401,929
+121% +$2.92M
SYRS
89
DELISTED
Syros Pharmaceuticals, Inc. Common Stock
SYRS
$5.16M 0.02%
690,167
– –
ITOS
90
DELISTED
iTeos Therapeutics
ITOS
$5.14M 0.02%
150,346
– –
DNLI icon
91
Denali Therapeutics
DNLI
$2.31B
$5.07M 0.02%
88,738
– –
ALEC icon
92
Alector
ALEC
$279M
$4.82M 0.02%
239,228
– –
EVFM
93
DELISTED
Evofem Biosciences, Inc. Common Stock
EVFM
$4.72M 0.02%
2,697,110
+2,285,714
+556% +$4M
REPL icon
94
Replimune Group
REPL
$476M
$4.68M 0.02%
153,512
– –
TVTX icon
95
Travere Therapeutics
TVTX
$1.71B
$4.67M 0.02%
+186,915
New +$4.67M
SRPT icon
96
Sarepta Therapeutics
SRPT
$1.93B
$4.38M 0.02%
+58,700
New +$4.38M
PASG icon
97
Passage Bio
PASG
$23.2M
$4.11M 0.02%
235,362
– –
HRMY icon
98
Harmony Biosciences
HRMY
$2.13B
$4.08M 0.02%
123,600
-56,400
-31% -$1.86M
TCRR
99
DELISTED
TCR2 Therapeutics Inc. Common Stock
TCRR
$3.9M 0.02%
176,461
+65,573
+59% +$1.45M
TCDA
100
DELISTED
Tricida, Inc. Common Stock
TCDA
$3.86M 0.02%
729,300
+100,000
+16% +$529K
2 3
4
5 6