BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
-0.11%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$7.97B
AUM Growth
+$7.97B
Cap. Flow
+$3.4M
Cap. Flow %
0.04%
Top 10 Hldgs %
77.13%
Holding
96
New
12
Increased
15
Reduced
7
Closed
7

Top Buys

1
BCYC
Bicycle Therapeutics
BCYC
$78.5M
2
RVMD icon
Revolution Medicines
RVMD
$77.4M
3
EWTX icon
Edgewise Therapeutics
EWTX
$49.7M
4
DNLI icon
Denali Therapeutics
DNLI
$23.1M
5
CELC icon
Celcuity
CELC
$22M

Top Sells

1
MRTX
Mirati Therapeutics, Inc. Common Stock
MRTX
$242M
2
IMCR icon
Immunocore
IMCR
$65.4M
3
GRCL
Gracell Biotechnologies Inc. American Depositary Shares
GRCL
$20.9M
4
DAWN icon
Day One Biopharmaceuticals
DAWN
$14.6M
5
SPRY icon
ARS Pharmaceuticals
SPRY
$11M

Sector Composition

1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
OPT
51
DELISTED
Opthea Limited American Depositary Shares
OPT
$8.95M 0.11%
2,177,826
-410,819
-16% -$1.69M
NMRA icon
52
Neumora Therapeutics
NMRA
$283M
$8.72M 0.11%
+633,851
New +$8.72M
ATHA icon
53
Athira Pharma
ATHA
$15.5M
$8.64M 0.11%
3,153,807
– –
DYN icon
54
Dyne Therapeutics
DYN
$1.92B
$8.09M 0.1%
+285,000
New +$8.09M
PRAX icon
55
Praxis Precision Medicines
PRAX
$980M
$8.03M 0.1%
131,533
– –
SAGE
56
DELISTED
Sage Therapeutics
SAGE
$7.63M 0.1%
+407,217
New +$7.63M
SGMT icon
57
Sagimet Biosciences
SGMT
$239M
$7.49M 0.09%
1,381,898
-74,620
-5% -$404K
PRME icon
58
Prime Medicine
PRME
$595M
$7.2M 0.09%
1,028,466
– –
DSGN icon
59
Design Therapeutics
DSGN
$339M
$6.7M 0.08%
1,662,120
+162,120
+11% +$653K
TNGX icon
60
Tango Therapeutics
TNGX
$745M
$5.96M 0.07%
750,000
– –
HOOK
61
DELISTED
HOOKIPA Pharma
HOOK
$5.79M 0.07%
8,128,151
– –
MRSN icon
62
Mersana Therapeutics
MRSN
$34.8M
$4.87M 0.06%
1,086,115
– –
MIRM icon
63
Mirum Pharmaceuticals
MIRM
$3.75B
$4.78M 0.06%
190,476
– –
TLIS
64
DELISTED
Talis Biomedical Corporation Common Stock
TLIS
$4.45M 0.06%
508,323
– –
PCVX icon
65
Vaxcyte
PCVX
$4.17B
$3.34M 0.04%
48,885
– –
IPSC icon
66
Century Therapeutics
IPSC
$40.4M
$3.33M 0.04%
797,460
– –
ALPN
67
DELISTED
Alpine Immune Sciences, Inc. Common Stock
ALPN
$3.23M 0.04%
+81,578
New +$3.23M
FDMT icon
68
4D Molecular Therapeutics
FDMT
$302M
$3.19M 0.04%
+100,000
New +$3.19M
LPTX icon
69
Leap Therapeutics
LPTX
$12M
$3.12M 0.04%
1,172,175
– –
CMPX icon
70
Compass Therapeutics
CMPX
$466M
$3.08M 0.04%
1,557,630
– –
NAMS icon
71
NewAmsterdam Pharma
NAMS
$2.8B
$2.29M 0.03%
+96,827
New +$2.29M
VTVT icon
72
vTv Therapeutics
VTVT
$49.4M
$2.29M 0.03%
+97,314
New +$2.29M
KALA icon
73
KALA BIO
KALA
$105M
$2.12M 0.03%
266,613
– –
ALGS icon
74
Aligos Therapeutics
ALGS
$75.1M
$2.03M 0.03%
2,076,400
– –
ELVN icon
75
Enliven Therapeutics
ELVN
$1.24B
$2.02M 0.03%
+114,833
New +$2.02M
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