|
1
|
Farallon Capital Management
San Francisco,
California
|
$1.32B
|
-$98.8M
|
-978,000
|
-7%
|
|
|
2
|
|
$1.09B
|
+$231M
|
+2,286,050
|
+26%
|
|
|
3
|
Janus Henderson Group
London,
|
$950M
|
-$256M
|
-2,537,006
|
-21%
|
|
|
4
|
Baker Bros. Advisors
New York
|
$929M
|
+$10.1M
|
+100,000
|
+1%
|
|
|
5
|
Fidelity Investments
Boston,
Massachusetts
|
$823M
|
-$12.5M
|
-123,667
|
-1%
|
|
|
6
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$813M
|
+$844M
|
+8,362,284
|
New
|
|
|
7
|
Nextech Invest
Zurich,
Switzerland
|
$739M
|
–
|
–
|
–
|
|
|
8
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$730M
|
+$758M
|
+7,502,623
|
New
|
|
|
9
|
Paradigm Biocapital Advisors
New York
|
$647M
|
+$1.14M
|
+11,300
|
+0.2%
|
|
|
10
|
Wellington Management Group
Boston,
Massachusetts
|
$586M
|
-$96.9M
|
-959,820
|
-14%
|
|
|
11
|
Adage Capital Partners
Boston,
Massachusetts
|
$533M
|
+$330M
|
+3,270,056
|
+148%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$428M
|
+$29.6M
|
+293,372
|
+7%
|
|
|
13
|
UBS Group
Zurich,
Switzerland
|
$427M
|
+$131M
|
+1,298,854
|
+42%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$324M
|
+$17.8M
|
+176,179
|
+6%
|
|
|
15
|
Alphabet Inc
Mountain View,
California
|
$320M
|
-$5.31M
|
-52,577
|
-2%
|
|
|
16
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$314M
|
-$17.4M
|
-172,504
|
-5%
|
|
|
17
|
BVF Inc
San Francisco,
California
|
$278M
|
-$50.5M
|
-500,000
|
-15%
|
|
|
18
|
|
$251M
|
–
|
–
|
–
|
|
|
19
|
Woodline Partners
San Francisco,
California
|
$244M
|
+$573K
|
+5,675
|
+0.2%
|
|
|
20
|
Holocene Advisors
New York
|
$240M
|
+$56.6M
|
+560,696
|
+29%
|
|
|
21
|
Vestal Point Capital
New York
|
$231M
|
+$210M
|
+2,080,000
|
+705%
|
|
|
22
|
Avoro Capital Advisors
New York
|
$228M
|
+$17.6M
|
+174,444
|
+8%
|
|
|
23
|
Deerfield Management
New York
|
$223M
|
-$60.3M
|
-597,613
|
-21%
|
|
|
24
|
|
$213M
|
-$30.9M
|
-306,083
|
-12%
|
|
|
25
|
Darwin Global Management
St. Helier,
Jersey
|
$205M
|
+$223M
|
+2,211,018
|
New
|
|
