|
1
|
Vanguard Group
Malvern,
Pennsylvania
|
$476M
|
+$3.64M
|
+122,721
|
+0.8%
|
|
|
2
|
Wellington Management Group
Boston,
Massachusetts
|
$474M
|
-$4.96M
|
-167,360
|
-1%
|
|
|
3
|
|
$397M
|
-$19.2M
|
-646,312
|
-5%
|
|
|
4
|
Baker Bros. Advisors
New York
|
$243M
|
+$71.2M
|
+2,400,592
|
+47%
|
|
|
5
|
Farallon Capital Management
San Francisco,
California
|
$242M
|
+$22.9M
|
+771,018
|
+11%
|
|
|
6
|
Nextech Invest
Zurich,
Switzerland
|
$203M
|
–
|
–
|
–
|
|
|
7
|
BVF Inc
San Francisco,
California
|
$193M
|
–
|
–
|
–
|
|
|
8
|
|
$181M
|
-$2.88M
|
-97,176
|
-2%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$174M
|
-$25.7M
|
-867,341
|
-14%
|
|
|
10
|
Alphabet Inc
Mountain View,
California
|
$171M
|
–
|
–
|
–
|
|
|
11
|
Bellevue Group
Kuesnacht,
Switzerland
|
$164M
|
-$516K
|
-17,400
|
-0.3%
|
|
|
12
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$155M
|
+$5.27M
|
+177,957
|
+4%
|
|
|
13
|
Boxer Capital
San Diego,
California
|
$138M
|
–
|
–
|
–
|
|
|
14
|
Fidelity Investments
Boston,
Massachusetts
|
$134M
|
+$77.5K
|
+2,615
|
+0.1%
|
|
|
15
|
Janus Henderson Group
London,
|
$126M
|
+$50.8M
|
+1,712,639
|
+78%
|
|
|
16
|
Woodline Partners
San Francisco,
California
|
$122M
|
+$24.8M
|
+837,108
|
+28%
|
|
|
17
|
|
$113M
|
-$26.2M
|
-882,525
|
-20%
|
|
|
18
|
Deerfield Management
New York
|
$99.6M
|
–
|
–
|
–
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$98.4M
|
+$2.19M
|
+73,907
|
+2%
|
|
|
20
|
Paradigm Biocapital Advisors
New York
|
$93.9M
|
+$86.4M
|
+2,914,975
|
New
|
|
|
21
|
AH Capital Management
Menlo Park,
California
|
$88.6M
|
-$87.4M
|
-2,948,544
|
-52%
|
|
|
22
|
Holocene Advisors
New York
|
$78.1M
|
-$13.6M
|
-459,744
|
-16%
|
|
|
23
|
|
$55.1M
|
+$42.3M
|
+1,426,571
|
+506%
|
|
|
24
|
Ameriprise
Minneapolis,
Minnesota
|
$54.6M
|
+$2.12M
|
+71,480
|
+4%
|
|
|
25
|
Balyasny Asset Management
Chicago,
Illinois
|
$53.3M
|
+$32.2M
|
+1,087,790
|
+192%
|
|
