|
1
|
Vanguard Group
Malvern,
Pennsylvania
|
$1.33B
|
+$69.3M
|
+1,056,792
|
+7%
|
|
|
2
|
Farallon Capital Management
San Francisco,
California
|
$1.16B
|
-$2.81M
|
-42,896
|
-0.3%
|
|
|
3
|
Janus Henderson Group
London,
|
$980M
|
+$62.1M
|
+947,448
|
+8%
|
|
|
4
|
Baker Bros. Advisors
New York
|
$753M
|
–
|
–
|
–
|
|
|
5
|
|
$711M
|
+$39.3M
|
+598,898
|
+7%
|
|
|
6
|
Fidelity Investments
Boston,
Massachusetts
|
$684M
|
-$53.4M
|
-813,706
|
-9%
|
|
|
7
|
Nextech Invest
Zurich,
Switzerland
|
$605M
|
–
|
–
|
–
|
|
|
8
|
Wellington Management Group
Boston,
Massachusetts
|
$557M
|
-$185M
|
-2,825,797
|
-29%
|
|
|
9
|
Paradigm Biocapital Advisors
New York
|
$529M
|
+$27.6M
|
+421,112
|
+7%
|
|
|
10
|
Bellevue Group
Kuesnacht,
Switzerland
|
$399M
|
-$37.3M
|
-568,119
|
-10%
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$327M
|
-$75.1M
|
-1,145,349
|
-22%
|
|
|
12
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$271M
|
-$30.8M
|
-468,989
|
-12%
|
|
|
13
|
BVF Inc
San Francisco,
California
|
$267M
|
-$40.5M
|
-618,131
|
-16%
|
|
|
14
|
Alphabet Inc
Mountain View,
California
|
$266M
|
-$51.7M
|
-788,175
|
-19%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$252M
|
+$1.07M
|
+16,323
|
+0.5%
|
|
|
16
|
UBS Group
Zurich,
Switzerland
|
$246M
|
+$131M
|
+1,998,972
|
+184%
|
|
|
17
|
Deerfield Management
New York
|
$231M
|
-$49.6M
|
-755,729
|
-21%
|
|
|
18
|
Westfield Capital Management
Boston,
Massachusetts
|
$227M
|
+$21.7M
|
+331,046
|
+13%
|
|
|
19
|
General Atlantic
New York
|
$224M
|
+$22.2M
|
+338,500
|
+14%
|
|
|
20
|
|
$205M
|
-$4.59M
|
-70,000
|
-3%
|
|
|
21
|
Woodline Partners
San Francisco,
California
|
$199M
|
-$27.2M
|
-414,988
|
-14%
|
|
|
22
|
|
$198M
|
+$115M
|
+1,753,557
|
+238%
|
|
|
23
|
|
$196M
|
+$161M
|
+2,455,347
|
New
|
|
|
24
|
Adage Capital Partners
Boston,
Massachusetts
|
$176M
|
+$95.9M
|
+1,463,155
|
+197%
|
|
|
25
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$175M
|
-$169M
|
-2,581,942
|
-54%
|
|
