|
1
|
TRV GP III
Boston,
Massachusetts
|
$198M
|
+$250M
|
+9,024,031
|
New
|
|
|
2
|
|
$175M
|
+$221M
|
+7,977,384
|
New
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$144M
|
+$184M
|
+6,664,063
|
New
|
|
|
4
|
Boxer Capital
San Diego,
California
|
$66.8M
|
+$84.4M
|
+3,049,764
|
New
|
|
|
5
|
Cormorant Asset Management
Boston,
Massachusetts
|
$60.6M
|
+$76.6M
|
+2,767,078
|
New
|
|
|
6
|
TRV GP II
Boston,
Massachusetts
|
$41.8M
|
+$52.9M
|
+1,909,317
|
New
|
|
|
7
|
Deerfield Management
New York
|
$39.4M
|
+$49.7M
|
+1,796,383
|
New
|
|
|
8
|
TRV GP IV
Boston,
Massachusetts
|
$31.1M
|
+$39.3M
|
+1,419,900
|
New
|
|
|
9
|
BVF Inc
San Francisco,
California
|
$30.6M
|
+$38.7M
|
+1,398,070
|
New
|
|
|
10
|
|
$28.9M
|
+$36.5M
|
+1,319,536
|
New
|
|
|
11
|
Vanguard Group
Malvern,
Pennsylvania
|
$23.9M
|
+$30.2M
|
+1,089,650
|
New
|
|
|
12
|
Capital World Investors
Los Angeles,
California
|
$19.1M
|
+$24.1M
|
+869,534
|
New
|
|
|
13
|
|
$17.5M
|
+$22.1M
|
+798,257
|
New
|
|
|
14
|
Bessemer Group
Woodbridge,
New Jersey
|
$14.8M
|
+$18.7M
|
+675,418
|
New
|
|
|
15
|
Harvard Management Company
Boston,
Massachusetts
|
$14.7M
|
+$18.6M
|
+670,382
|
New
|
|
|
16
|
|
$11.2M
|
+$14.2M
|
+513,131
|
New
|
|
|
17
|
Avoro Capital Advisors
New York
|
$9.86M
|
+$12.5M
|
+450,000
|
New
|
|
|
18
|
Perceptive Advisors
New York
|
$7.82M
|
+$9.69M
|
+350,000
|
New
|
|
|
19
|
Franklin Resources
San Mateo,
California
|
$7.67M
|
+$9.69M
|
+350,000
|
New
|
|
|
20
|
Citadel Advisors
Miami,
Florida
|
$7.64M
|
+$9.65M
|
+348,642
|
New
|
|
|
21
|
Wellington Management Group
Boston,
Massachusetts
|
$7.38M
|
+$9.32M
|
+336,665
|
New
|
|
|
22
|
Redmile Group
San Francisco,
California
|
$6.65M
|
+$8.4M
|
+303,371
|
New
|
|
|
23
|
|
$6.57M
|
+$8.3M
|
+300,000
|
New
|
|
|
24
|
State Street
Boston,
Massachusetts
|
$5.18M
|
+$6.55M
|
+236,451
|
New
|
|
|
25
|
Jennison Associates
New York
|
$4.39M
|
+$5.55M
|
+200,490
|
New
|
|
