|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$497M
|
+$66.9M
|
+1,492,760
|
+16%
|
|
|
2
|
TRV GP III
Boston,
Massachusetts
|
$253M
|
-$67.3M
|
-1,500,000
|
-21%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$223M
|
+$36.4M
|
+812,442
|
+20%
|
|
|
4
|
Wellington Management Group
Boston,
Massachusetts
|
$180M
|
+$165M
|
+3,688,457
|
+1,589%
|
|
|
5
|
|
$176M
|
+$14.3M
|
+318,987
|
+9%
|
|
|
6
|
Column Group
San Francisco,
California
|
$164M
|
–
|
–
|
–
|
|
|
7
|
Boxer Capital
San Diego,
California
|
$160M
|
+$7.85M
|
+175,000
|
+5%
|
|
|
8
|
BVF Inc
San Francisco,
California
|
$135M
|
+$7.85M
|
+175,000
|
+6%
|
|
|
9
|
Cormorant Asset Management
Boston,
Massachusetts
|
$116M
|
+$1.34M
|
+29,934
|
+1%
|
|
|
10
|
TRV GP II
Boston,
Massachusetts
|
$87.6M
|
–
|
–
|
–
|
|
|
11
|
|
$84.6M
|
+$9.42M
|
+210,000
|
+13%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$81.6M
|
-$581K
|
-12,952
|
-0.7%
|
|
|
13
|
Farallon Capital Management
San Francisco,
California
|
$73.9M
|
+$72.2M
|
+1,609,730
|
New
|
|
|
14
|
Deerfield Management
New York
|
$65.9M
|
+$1.81M
|
+40,329
|
+3%
|
|
|
15
|
TRV GP IV
Boston,
Massachusetts
|
$65.1M
|
–
|
–
|
–
|
|
|
16
|
|
$56.7M
|
+$3.41M
|
+76,031
|
+7%
|
|
|
17
|
Capital World Investors
Los Angeles,
California
|
$56.3M
|
–
|
–
|
–
|
|
|
18
|
Citadel Advisors
Miami,
Florida
|
$51.3M
|
-$5.49M
|
-122,484
|
-10%
|
|
|
19
|
Bellevue Group
Kuesnacht,
Switzerland
|
$48.9M
|
+$46M
|
+1,025,770
|
+2,564%
|
|
|
20
|
Woodline Partners
San Francisco,
California
|
$38.6M
|
+$1.57M
|
+34,932
|
+4%
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$35.7M
|
+$6.11M
|
+136,235
|
+21%
|
|
|
22
|
Victory Capital Management
San Antonio,
Texas
|
$34.7M
|
+$31.7M
|
+707,459
|
+1,462%
|
|
|
23
|
|
$32.4M
|
+$8.95M
|
+199,625
|
+39%
|
|
|
24
|
Ponoi II Management
San Francisco,
California
|
$31.4M
|
–
|
–
|
–
|
|
|
25
|
Ponoi Management
San Francisco,
California
|
$31.4M
|
–
|
–
|
–
|
|
