|
1
|
Vanguard Group
Malvern,
Pennsylvania
|
$748M
|
+$110M
|
+2,185,082
|
+15%
|
|
|
2
|
|
$644M
|
+$43M
|
+852,690
|
+6%
|
|
|
3
|
Farallon Capital Management
San Francisco,
California
|
$579M
|
+$97.5M
|
+1,931,000
|
+17%
|
|
|
4
|
Wellington Management Group
Boston,
Massachusetts
|
$473M
|
-$29.3M
|
-579,703
|
-5%
|
|
|
5
|
Janus Henderson Group
London,
|
$415M
|
+$169M
|
+3,346,755
|
+55%
|
|
|
6
|
Baker Bros. Advisors
New York
|
$347M
|
+$18.6M
|
+367,882
|
+5%
|
|
|
7
|
Nextech Invest
Zurich,
Switzerland
|
$332M
|
+$65.8M
|
+1,304,347
|
+21%
|
|
|
8
|
Fidelity Investments
Boston,
Massachusetts
|
$295M
|
+$43.7M
|
+866,190
|
+15%
|
|
|
9
|
Paradigm Biocapital Advisors
New York
|
$287M
|
+$62.5M
|
+1,239,022
|
+23%
|
|
|
10
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$257M
|
+$27.9M
|
+552,657
|
+10%
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$253M
|
+$25.8M
|
+512,168
|
+10%
|
|
|
12
|
Bellevue Group
Kuesnacht,
Switzerland
|
$192M
|
-$24.4M
|
-484,460
|
-10%
|
|
|
13
|
Boxer Capital Management
San Diego,
California
|
$187M
|
+$216M
|
+4,279,464
|
New
|
|
|
14
|
BVF Inc
San Francisco,
California
|
$183M
|
+$35.5M
|
+702,567
|
+20%
|
|
|
15
|
Alphabet Inc
Mountain View,
California
|
$181M
|
-$6.2M
|
-122,898
|
-3%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$180M
|
+$23.2M
|
+459,174
|
+13%
|
|
|
17
|
Woodline Partners
San Francisco,
California
|
$170M
|
+$22.8M
|
+452,000
|
+13%
|
|
|
18
|
|
$167M
|
-$15.6M
|
-308,571
|
-7%
|
|
|
19
|
|
$162M
|
-$20.9M
|
-415,000
|
-10%
|
|
|
20
|
Deerfield Management
New York
|
$143M
|
+$17.4M
|
+345,640
|
+12%
|
|
|
21
|
Holocene Advisors
New York
|
$131M
|
+$42.8M
|
+847,149
|
+39%
|
|
|
22
|
AH Capital Management
Menlo Park,
California
|
$120M
|
–
|
–
|
–
|
|
|
23
|
|
$115M
|
+$13.9M
|
+275,550
|
+12%
|
|
|
24
|
Lunate Holding RSC
Al Maryah Island, Abu Dhabi,
United Arab Emirates
|
$96.1M
|
+$111M
|
+2,196,200
|
New
|
|
|
25
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$86.5M
|
+$7.4M
|
+146,699
|
+8%
|
|
