|
1
|
Wellington Management Group
Boston,
Massachusetts
|
$293M
|
+$8.39M
|
+282,786
|
+3%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$267M
|
+$8.99M
|
+303,088
|
+3%
|
|
|
3
|
|
$246M
|
+$18.2M
|
+613,798
|
+7%
|
|
|
4
|
EcoR1 Capital
San Francisco,
California
|
$154M
|
-$48.1M
|
-1,620,837
|
-23%
|
|
|
5
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$141M
|
+$2.25M
|
+75,941
|
+2%
|
|
|
6
|
Nextech Invest
Zurich,
Switzerland
|
$134M
|
–
|
–
|
–
|
|
|
7
|
Bellevue Group
Kuesnacht,
Switzerland
|
$131M
|
-$727K
|
-24,500
|
-0.5%
|
|
|
8
|
Boxer Capital
San Diego,
California
|
$130M
|
–
|
–
|
–
|
|
|
9
|
|
$118M
|
+$9.26M
|
+312,166
|
+8%
|
|
|
10
|
BVF Inc
San Francisco,
California
|
$110M
|
-$67.5M
|
-2,274,376
|
-36%
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$107M
|
-$26M
|
-876,639
|
-18%
|
|
|
12
|
Farallon Capital Management
San Francisco,
California
|
$92M
|
+$16.1M
|
+542,000
|
+19%
|
|
|
13
|
Woodline Partners
San Francisco,
California
|
$87.1M
|
-$18.3M
|
-615,930
|
-16%
|
|
|
14
|
Baker Bros. Advisors
New York
|
$74.5M
|
–
|
–
|
–
|
|
|
15
|
|
$70M
|
+$3.8M
|
+128,120
|
+5%
|
|
|
16
|
Janus Henderson Group
London,
|
$62M
|
+$27.4M
|
+922,897
|
+70%
|
|
|
17
|
Holocene Advisors
New York
|
$60.6M
|
+$376K
|
+12,662
|
+0.6%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$57.4M
|
+$3.69M
|
+124,272
|
+6%
|
|
|
19
|
|
$50.1M
|
–
|
–
|
–
|
|
|
20
|
Deerfield Management
New York
|
$48.5M
|
–
|
–
|
–
|
|
|
21
|
Dimensional Fund Advisors
Austin,
Texas
|
$46M
|
-$205K
|
-6,913
|
-0.4%
|
|
|
22
|
Perceptive Advisors
New York
|
$36.6M
|
+$39.2M
|
+1,321,795
|
New
|
|
|
23
|
Column Group
San Francisco,
California
|
$34.1M
|
-$39.9M
|
-1,346,579
|
-52%
|
|
|
24
|
Ameriprise
Minneapolis,
Minnesota
|
$33.5M
|
-$352K
|
-11,869
|
-1%
|
|
|
25
|
Frazier Life Sciences Management
Palo Alto,
California
|
$27.6M
|
+$4.24M
|
+142,971
|
+17%
|
|
