|
1
|
Vanguard Group
Malvern,
Pennsylvania
|
$159M
|
+$1.67M
|
+59,411
|
+1%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$154M
|
-$47.8M
|
-1,696,160
|
-22%
|
|
|
3
|
TRV GP III
Boston,
Massachusetts
|
$139M
|
–
|
–
|
–
|
|
|
4
|
|
$138M
|
+$10.4M
|
+369,181
|
+7%
|
|
|
5
|
Wellington Management Group
Boston,
Massachusetts
|
$114M
|
-$739K
|
-26,207
|
-0.6%
|
|
|
6
|
Boxer Capital
San Diego,
California
|
$87.7M
|
–
|
–
|
–
|
|
|
7
|
Bellevue Group
Kuesnacht,
Switzerland
|
$87.3M
|
+$320K
|
+11,357
|
+0.3%
|
|
|
8
|
Column Group
San Francisco,
California
|
$84.3M
|
–
|
–
|
–
|
|
|
9
|
Nextech Invest
Zurich,
Switzerland
|
$74.7M
|
+$83.7M
|
+2,968,214
|
New
|
|
|
10
|
Woodline Partners
San Francisco,
California
|
$73.7M
|
+$58.1M
|
+2,060,554
|
+237%
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$69.3M
|
-$1.54M
|
-54,539
|
-2%
|
|
|
12
|
Farallon Capital Management
San Francisco,
California
|
$69.2M
|
–
|
–
|
–
|
|
|
13
|
Cormorant Asset Management
Boston,
Massachusetts
|
$61.2M
|
-$20.1M
|
-712,848
|
-23%
|
|
|
14
|
|
$59.7M
|
-$12.1M
|
-430,000
|
-15%
|
|
|
15
|
BVF Inc
San Francisco,
California
|
$45.6M
|
-$19M
|
-674,500
|
-27%
|
|
|
16
|
TRV GP IV
Boston,
Massachusetts
|
$35.7M
|
–
|
–
|
–
|
|
|
17
|
|
$32.3M
|
-$1.04M
|
-36,943
|
-3%
|
|
|
18
|
Capital World Investors
Los Angeles,
California
|
$30.9M
|
–
|
–
|
–
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$27.8M
|
+$636K
|
+22,558
|
+2%
|
|
|
20
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$26.6M
|
+$1.01M
|
+35,925
|
+4%
|
|
|
21
|
Ameriprise
Minneapolis,
Minnesota
|
$24.2M
|
+$58.3K
|
+2,069
|
+0.2%
|
|
|
22
|
Deerfield Management
New York
|
$22.4M
|
-$19M
|
-674,125
|
-43%
|
|
|
23
|
|
$17.5M
|
-$7.88M
|
-279,695
|
-29%
|
|
|
24
|
Ponoi II Management
San Francisco,
California
|
$17.2M
|
–
|
–
|
–
|
|
|
25
|
Ponoi Management
San Francisco,
California
|
$17.2M
|
–
|
–
|
–
|
|
