|
1
|
Vanguard Group
Malvern,
Pennsylvania
|
$676M
|
+$23.2M
|
+533,076
|
+4%
|
|
|
2
|
|
$629M
|
+$19.9M
|
+458,145
|
+3%
|
|
|
3
|
Wellington Management Group
Boston,
Massachusetts
|
$517M
|
-$98.4M
|
-2,258,802
|
-17%
|
|
|
4
|
Farallon Capital Management
San Francisco,
California
|
$513M
|
+$67.9M
|
+1,560,000
|
+16%
|
|
|
5
|
Baker Bros. Advisors
New York
|
$343M
|
–
|
–
|
–
|
|
|
6
|
Nextech Invest
Zurich,
Switzerland
|
$286M
|
–
|
–
|
–
|
|
|
7
|
Janus Henderson Group
London,
|
$278M
|
+$65.2M
|
+1,497,026
|
+32%
|
|
|
8
|
Fidelity Investments
Boston,
Massachusetts
|
$266M
|
+$10.9M
|
+250,037
|
+4%
|
|
|
9
|
Paradigm Biocapital Advisors
New York
|
$241M
|
+$2.39M
|
+55,000
|
+1%
|
|
|
10
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$241M
|
+$4.21M
|
+96,646
|
+2%
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$239M
|
+$9.08M
|
+208,516
|
+4%
|
|
|
12
|
Bellevue Group
Kuesnacht,
Switzerland
|
$221M
|
-$6.87M
|
-157,740
|
-3%
|
|
|
13
|
Boxer Capital
San Diego,
California
|
$194M
|
–
|
–
|
–
|
|
|
14
|
Alphabet Inc
Mountain View,
California
|
$193M
|
-$45.8M
|
-1,050,900
|
-20%
|
|
|
15
|
|
$188M
|
+$44.5M
|
+1,022,345
|
+33%
|
|
|
16
|
|
$187M
|
-$12.7M
|
-292,592
|
-7%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$165M
|
+$12.7M
|
+291,369
|
+9%
|
|
|
18
|
BVF Inc
San Francisco,
California
|
$158M
|
-$109M
|
-2,502,600
|
-42%
|
|
|
19
|
Woodline Partners
San Francisco,
California
|
$156M
|
+$6.22M
|
+142,922
|
+4%
|
|
|
20
|
Deerfield Management
New York
|
$132M
|
-$7.72M
|
-177,381
|
-6%
|
|
|
21
|
AH Capital Management
Menlo Park,
California
|
$125M
|
–
|
–
|
–
|
|
|
22
|
|
$107M
|
+$39.5M
|
+906,507
|
+63%
|
|
|
23
|
Holocene Advisors
New York
|
$97.5M
|
-$2.35M
|
-53,913
|
-2%
|
|
|
24
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$83.1M
|
+$79.8M
|
+1,832,021
|
New
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
$80M
|
+$28.5M
|
+653,433
|
+59%
|
|
