|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$370M
|
-$21.7M
|
-549,476
|
-6%
|
|
|
2
|
TRV GP III
Boston,
Massachusetts
|
$278M
|
-$39.5M
|
-1,000,000
|
-12%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$160M
|
+$23.2M
|
+587,719
|
+17%
|
|
|
4
|
Column Group
San Francisco,
California
|
$142M
|
+$142M
|
+3,580,252
|
New
|
|
|
5
|
|
$139M
|
+$38.6M
|
+975,677
|
+38%
|
|
|
6
|
Boxer Capital
San Diego,
California
|
$131M
|
–
|
–
|
–
|
|
|
7
|
BVF Inc
San Francisco,
California
|
$110M
|
+$26.4M
|
+667,000
|
+32%
|
|
|
8
|
Cormorant Asset Management
Boston,
Massachusetts
|
$98.8M
|
-$5.74M
|
-145,111
|
-5%
|
|
|
9
|
TRV GP II
Boston,
Massachusetts
|
$75.6M
|
–
|
–
|
–
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$70.9M
|
+$28.5M
|
+720,230
|
+67%
|
|
|
11
|
|
$64.7M
|
–
|
–
|
–
|
|
|
12
|
TRV GP IV
Boston,
Massachusetts
|
$56.2M
|
–
|
–
|
–
|
|
|
13
|
Deerfield Management
New York
|
$55.3M
|
-$15.8M
|
-400,000
|
-22%
|
|
|
14
|
Citadel Advisors
Miami,
Florida
|
$49.1M
|
+$34.2M
|
+865,211
|
+231%
|
|
|
15
|
Capital World Investors
Los Angeles,
California
|
$48.6M
|
–
|
–
|
–
|
|
|
16
|
|
$45.9M
|
+$1.94M
|
+49,137
|
+4%
|
|
|
17
|
Woodline Partners
San Francisco,
California
|
$32M
|
+$30.8M
|
+779,219
|
+2,792%
|
|
|
18
|
Ponoi II Management
San Francisco,
California
|
$27.1M
|
+$27.1M
|
+685,011
|
New
|
|
|
19
|
Ponoi Management
San Francisco,
California
|
$27.1M
|
+$27.1M
|
+685,011
|
New
|
|
|
20
|
Harvard Management Company
Boston,
Massachusetts
|
$26.5M
|
–
|
–
|
–
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$25.4M
|
+$643K
|
+16,265
|
+3%
|
|
|
22
|
Bessemer Group
Woodbridge,
New Jersey
|
$21.8M
|
-$4.91M
|
-124,167
|
-18%
|
|
|
23
|
|
$20.1M
|
+$17.9M
|
+453,272
|
+843%
|
|
|
24
|
Northern Trust
Chicago,
Illinois
|
$17.6M
|
-$296K
|
-7,498
|
-2%
|
|
|
25
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$15.4M
|
-$9.65M
|
-244,084
|
-39%
|
|
