|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$344M
|
+$55M
|
+1,985,236
|
+25%
|
|
|
2
|
TRV GP III
Boston,
Massachusetts
|
$279M
|
-$27.7M
|
-1,000,000
|
-11%
|
|
|
3
|
|
$278M
|
–
|
–
|
–
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$120M
|
+$59M
|
+2,131,334
|
+162%
|
|
|
5
|
Boxer Capital
San Diego,
California
|
$115M
|
+$9.69M
|
+350,000
|
+12%
|
|
|
6
|
Cormorant Asset Management
Boston,
Massachusetts
|
$91.9M
|
+$97.4K
|
+3,516
|
+0.1%
|
|
|
7
|
|
$88.3M
|
+$39.6M
|
+1,430,172
|
+129%
|
|
|
8
|
BVF Inc
San Francisco,
California
|
$73.1M
|
+$36.1M
|
+1,302,763
|
+163%
|
|
|
9
|
TRV GP II
Boston,
Massachusetts
|
$66.4M
|
–
|
–
|
–
|
|
|
10
|
Deerfield Management
New York
|
$62.5M
|
–
|
–
|
–
|
|
|
11
|
|
$56.9M
|
+$8.31M
|
+299,999
|
+22%
|
|
|
12
|
TRV GP IV
Boston,
Massachusetts
|
$49.4M
|
–
|
–
|
–
|
|
|
13
|
Capital World Investors
Los Angeles,
California
|
$42.7M
|
+$8.52M
|
+307,547
|
+33%
|
|
|
14
|
|
$37.7M
|
+$9.36M
|
+337,784
|
+44%
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$37.3M
|
+$22.4M
|
+808,613
|
+308%
|
|
|
16
|
Bessemer Group
Woodbridge,
New Jersey
|
$23.5M
|
–
|
–
|
–
|
|
|
17
|
Harvard Management Company
Boston,
Massachusetts
|
$23.3M
|
–
|
–
|
–
|
|
|
18
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$22M
|
+$17.5M
|
+633,090
|
New
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$21.8M
|
+$10.3M
|
+370,940
|
+145%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$15.7M
|
+$7.07M
|
+255,285
|
+130%
|
|
|
21
|
Citadel Advisors
Miami,
Florida
|
$13M
|
-$1.31M
|
-47,471
|
-11%
|
|
|
22
|
Franklin Resources
San Mateo,
California
|
$12.6M
|
+$341K
|
+12,300
|
+4%
|
|
|
23
|
PFM Health Sciences
San Francisco,
California
|
$12.5M
|
+$9.98M
|
+360,313
|
New
|
|
|
24
|
Charles Schwab
San Francisco,
California
|
$9.21M
|
+$4.63M
|
+167,008
|
+171%
|
|
|
25
|
Cresset Asset Management
Chicago,
Illinois
|
$8.31M
|
+$6.61M
|
+238,695
|
New
|
|
