|
1
|
Vanguard Group
Malvern,
Pennsylvania
|
$155M
|
-$5.26M
|
-241,678
|
-4%
|
|
|
2
|
TRV GP III
Boston,
Massachusetts
|
$141M
|
–
|
–
|
–
|
|
|
3
|
|
$136M
|
-$2.94M
|
-134,931
|
-2%
|
|
|
4
|
Wellington Management Group
Boston,
Massachusetts
|
$104M
|
-$9.29M
|
-426,906
|
-9%
|
|
|
5
|
Nextech Invest
Zurich,
Switzerland
|
$100M
|
+$21.1M
|
+971,315
|
+33%
|
|
|
6
|
Boxer Capital
San Diego,
California
|
$88.9M
|
–
|
–
|
–
|
|
|
7
|
Column Group
San Francisco,
California
|
$85.4M
|
–
|
–
|
–
|
|
|
8
|
Bellevue Group
Kuesnacht,
Switzerland
|
$84.5M
|
-$3.47M
|
-159,500
|
-5%
|
|
|
9
|
Farallon Capital Management
San Francisco,
California
|
$82.9M
|
+$10.9M
|
+500,000
|
+18%
|
|
|
10
|
Fidelity Investments
Boston,
Massachusetts
|
$73.1M
|
-$70.4M
|
-3,234,704
|
-53%
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$72.5M
|
+$1.93M
|
+88,844
|
+3%
|
|
|
12
|
|
$60.5M
|
–
|
–
|
–
|
|
|
13
|
Woodline Partners
San Francisco,
California
|
$59.5M
|
-$13M
|
-598,643
|
-20%
|
|
|
14
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$58.7M
|
+$27.1M
|
+1,244,045
|
+118%
|
|
|
15
|
Cormorant Asset Management
Boston,
Massachusetts
|
$50.9M
|
-$9.51M
|
-436,786
|
-18%
|
|
|
16
|
BVF Inc
San Francisco,
California
|
$46.2M
|
–
|
–
|
–
|
|
|
17
|
TRV GP IV
Boston,
Massachusetts
|
$36.2M
|
–
|
–
|
–
|
|
|
18
|
|
$34.2M
|
+$1.28M
|
+58,914
|
+5%
|
|
|
19
|
EcoR1 Capital
San Francisco,
California
|
$32.5M
|
+$27.7M
|
+1,274,097
|
New
|
|
|
20
|
Capital World Investors
Los Angeles,
California
|
$31.3M
|
–
|
–
|
–
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$28.6M
|
+$380K
|
+17,444
|
+2%
|
|
|
22
|
Ameriprise
Minneapolis,
Minnesota
|
$24.8M
|
+$201K
|
+9,218
|
+1%
|
|
|
23
|
Deerfield Management
New York
|
$22.7M
|
–
|
–
|
–
|
|
|
24
|
|
$22.2M
|
+$3.82M
|
+175,304
|
+25%
|
|
|
25
|
Ponoi II Management
San Francisco,
California
|
$17.5M
|
–
|
–
|
–
|
|
