|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$169M
|
+$7.93M
|
+281,302
|
+4%
|
|
|
2
|
|
$114M
|
+$61.8M
|
+2,194,677
|
+84%
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$99.1M
|
+$15M
|
+531,460
|
+15%
|
|
|
4
|
State Street
Boston,
Massachusetts
|
$77.1M
|
+$19.3M
|
+685,238
|
+27%
|
|
|
5
|
|
$76.9M
|
-$999K
|
-35,462
|
-1%
|
|
|
6
|
Point72 Asset Management
Stamford,
Connecticut
|
$69M
|
+$14M
|
+495,337
|
+20%
|
|
|
7
|
Johnson & Johnson
New Brunswick,
New Jersey
|
$58M
|
–
|
–
|
–
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$55.2M
|
-$510K
|
-18,092
|
-0.8%
|
|
|
9
|
|
$31.7M
|
+$34.6M
|
+1,229,687
|
+1,145%
|
|
|
10
|
Farallon Capital Management
San Francisco,
California
|
$26.9M
|
-$22.1M
|
-782,677
|
-41%
|
|
|
11
|
Dimensional Fund Advisors
Austin,
Texas
|
$20.4M
|
-$331K
|
-11,759
|
-1%
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$19.7M
|
+$1.55M
|
+54,840
|
+7%
|
|
|
13
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$19.5M
|
-$71.8K
|
-2,549
|
-0.3%
|
|
|
14
|
Obermeyer Wealth Partners
Aspen,
Colorado
|
$19M
|
+$357K
|
+12,683
|
+2%
|
|
|
15
|
|
$18.9M
|
-$12.7M
|
-449,900
|
-36%
|
|
|
16
|
Tri Locum Partners
New York
|
$18.2M
|
+$12.8M
|
+455,321
|
+145%
|
|
|
17
|
Cowen and Company
New York
|
$17.1M
|
+$20.3M
|
+719,397
|
+22,637%
|
|
|
18
|
Adage Capital Partners
Boston,
Massachusetts
|
$14.2M
|
+$4.23M
|
+150,000
|
+33%
|
|
|
19
|
Woodline Partners
San Francisco,
California
|
$13.9M
|
+$2.7M
|
+95,707
|
+19%
|
|
|
20
|
Fairmount Funds Management
West Conshohocken,
Pennsylvania
|
$13M
|
+$15.5M
|
+549,988
|
New
|
|
|
21
|
Sofinnova Investments
Menlo Park,
California
|
$13M
|
+$1.84M
|
+65,184
|
+14%
|
|
|
22
|
Millennium Management
New York
|
$10.9M
|
+$1.95M
|
+69,042
|
+18%
|
|
|
23
|
Northern Trust
Chicago,
Illinois
|
$10.3M
|
-$573K
|
-20,333
|
-4%
|
|
|
24
|
Altium Capital Management
New York
|
$9.14M
|
+$1.13M
|
+40,000
|
+12%
|
|
|
25
|
EcoR1 Capital
San Francisco,
California
|
$9.04M
|
-$63.6M
|
-2,257,995
|
-86%
|
|
