|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$234M
|
+$11.2M
|
+354,639
|
+5%
|
|
|
2
|
BVF Inc
San Francisco,
California
|
$125M
|
-$7.9M
|
-250,000
|
-6%
|
|
|
3
|
|
$112M
|
+$2.6M
|
+82,140
|
+3%
|
|
|
4
|
EcoR1 Capital
San Francisco,
California
|
$90.3M
|
+$37.8M
|
+1,195,906
|
+83%
|
|
|
5
|
|
$88.9M
|
+$26.7M
|
+846,127
|
+48%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$87.9M
|
+$17.6M
|
+557,591
|
+28%
|
|
|
7
|
Johnson & Johnson
New Brunswick,
New Jersey
|
$83.8M
|
–
|
–
|
–
|
|
|
8
|
Point72 Asset Management
Stamford,
Connecticut
|
$82.8M
|
-$62.2M
|
-1,967,537
|
-45%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$80.3M
|
-$178K
|
-5,620
|
-0.2%
|
|
|
10
|
Farallon Capital Management
San Francisco,
California
|
$65.6M
|
-$15M
|
-474,866
|
-20%
|
|
|
11
|
|
$42.8M
|
-$7.9M
|
-250,000
|
-17%
|
|
|
12
|
Deerfield Management
New York
|
$40.1M
|
-$6.99M
|
-221,057
|
-16%
|
|
|
13
|
Dimensional Fund Advisors
Austin,
Texas
|
$29.9M
|
-$34.2K
|
-1,081
|
-0.1%
|
|
|
14
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$28.2M
|
+$50K
|
+1,582
|
+0.2%
|
|
|
15
|
Commodore Capital
New York
|
$27.6M
|
+$9.72M
|
+307,494
|
+62%
|
|
|
16
|
Obermeyer Wealth Partners
Aspen,
Colorado
|
$27M
|
+$387K
|
+12,253
|
+2%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$26.6M
|
+$1.55M
|
+49,151
|
+7%
|
|
|
18
|
Woodline Partners
San Francisco,
California
|
$16.9M
|
+$15.6M
|
+492,987
|
New
|
|
|
19
|
Rothschild & Co Asset Management US
Stamford,
Connecticut
|
$16.8M
|
+$8.65M
|
+273,541
|
+126%
|
|
|
20
|
Sofinnova Investments
Menlo Park,
California
|
$16.5M
|
+$5.83M
|
+184,548
|
+62%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$15.6M
|
-$49.5K
|
-1,566
|
-0.3%
|
|
|
22
|
Adage Capital Partners
Boston,
Massachusetts
|
$15.4M
|
+$4.74M
|
+150,000
|
+50%
|
|
|
23
|
|
$15.4M
|
+$14.2M
|
+448,908
|
New
|
|
|
24
|
|
$14.9M
|
+$245K
|
+7,758
|
+2%
|
|
|
25
|
Mangrove Partners
Greenwich,
Connecticut
|
$14.8M
|
+$13.7M
|
+433,137
|
New
|
|
