|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$319M
|
+$18M
|
+545,156
|
+8%
|
|
|
2
|
BVF Inc
San Francisco,
California
|
$168M
|
-$6.78M
|
-205,356
|
-5%
|
|
|
3
|
|
$157M
|
–
|
–
|
–
|
|
|
4
|
Consonance Capital Management
New York
|
$155M
|
+$24.3M
|
+737,165
|
+27%
|
|
|
5
|
|
$136M
|
+$1.28M
|
+38,912
|
+1%
|
|
|
6
|
Johnson & Johnson Innovation - JJDC
New Brunswick,
New Jersey
|
$110M
|
–
|
–
|
–
|
|
|
7
|
Farallon Capital Management
San Francisco,
California
|
$105M
|
-$3.15M
|
-95,320
|
-4%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$103M
|
+$4.87M
|
+147,487
|
+7%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$65.3M
|
-$8.52M
|
-258,063
|
-15%
|
|
|
10
|
Deerfield Management
New York
|
$61.2M
|
+$3.43M
|
+104,000
|
+8%
|
|
|
11
|
Point72 Asset Management
Stamford,
Connecticut
|
$51.8M
|
+$7.03M
|
+212,900
|
+23%
|
|
|
12
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$44.3M
|
+$2.4M
|
+72,664
|
+8%
|
|
|
13
|
Victory Capital Management
San Antonio,
Texas
|
$37.9M
|
+$27.9M
|
+845,199
|
New
|
|
|
14
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$36.9M
|
+$26.3M
|
+796,161
|
+3,115%
|
|
|
15
|
Dimensional Fund Advisors
Austin,
Texas
|
$35.5M
|
+$4.45M
|
+134,915
|
+21%
|
|
|
16
|
Obermeyer Wealth Partners
Aspen,
Colorado
|
$34.2M
|
+$12.4M
|
+374,946
|
+97%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$32M
|
+$2.25M
|
+68,159
|
+11%
|
|
|
18
|
Novo Holdings A/S
Hellerup,
Denmark
|
$26.9M
|
-$8.84M
|
-267,714
|
-31%
|
|
|
19
|
Adage Capital Partners
Boston,
Massachusetts
|
$24.7M
|
-$1.65M
|
-50,000
|
-8%
|
|
|
20
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$24.1M
|
+$17.7M
|
+536,920
|
New
|
|
|
21
|
Baker Bros. Advisors
New York
|
$20.4M
|
-$32.4M
|
-980,916
|
-68%
|
|
|
22
|
Sofinnova Investments
Menlo Park,
California
|
$20.2M
|
-$6.79M
|
-205,818
|
-31%
|
|
|
23
|
Northern Trust
Chicago,
Illinois
|
$20M
|
+$960K
|
+29,072
|
+7%
|
|
|
24
|
|
$19.5M
|
-$5M
|
-151,469
|
-26%
|
|
|
25
|
Citadel Advisors
Miami,
Florida
|
$18.1M
|
+$6.77M
|
+204,990
|
+103%
|
|
