|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$47.3M
|
+$5.45M
|
+432,608
|
+12%
|
|
|
2
|
Farallon Capital Management
San Francisco,
California
|
$18M
|
–
|
–
|
–
|
|
|
3
|
Baker Bros. Advisors
New York
|
$14.1M
|
+$2.26M
|
+179,200
|
+18%
|
|
|
4
|
|
$13M
|
+$829K
|
+65,781
|
+6%
|
|
|
5
|
VHCP Management III
New York
|
$12.9M
|
–
|
–
|
–
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$11.2M
|
+$1.7M
|
+135,058
|
+17%
|
|
|
7
|
Millennium Management
New York
|
$10.1M
|
+$338K
|
+26,826
|
+3%
|
|
|
8
|
|
$9.15M
|
+$9.61M
|
+762,283
|
New
|
|
|
9
|
Dimensional Fund Advisors
Austin,
Texas
|
$8.78M
|
-$161K
|
-12,753
|
-2%
|
|
|
10
|
BVF Inc
San Francisco,
California
|
$8.2M
|
-$4.8M
|
-381,172
|
-36%
|
|
|
11
|
Renaissance Technologies
New York
|
$6.67M
|
+$539K
|
+42,800
|
+8%
|
|
|
12
|
Novo Holdings A/S
Hellerup,
Denmark
|
$5.75M
|
+$5.74M
|
+455,173
|
+1,904%
|
|
|
13
|
VHCP Management II
New York
|
$5.13M
|
–
|
–
|
–
|
|
|
14
|
Acuta Capital Partners
Redwood City,
California
|
$5.03M
|
-$3.19M
|
-253,000
|
-38%
|
|
|
15
|
Citadel Advisors
Miami,
Florida
|
$5M
|
+$80.8K
|
+6,408
|
+2%
|
|
|
16
|
|
$3.97M
|
-$846K
|
-67,109
|
-17%
|
|
|
17
|
State Street
Boston,
Massachusetts
|
$3.78M
|
+$660K
|
+52,333
|
+20%
|
|
|
18
|
|
$3.39M
|
-$3.49M
|
-276,570
|
-49%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$3.14M
|
+$722K
|
+57,322
|
+28%
|
|
|
20
|
Ghost Tree Capital
New York
|
$3M
|
+$630K
|
+50,000
|
+25%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$2.96M
|
+$2.22M
|
+176,269
|
+251%
|
|
|
22
|
Oxford Asset Management
Oxford,
United Kingdom
|
$2.07M
|
-$543K
|
-43,050
|
-20%
|
|
|
23
|
Point72 Asset Management
Stamford,
Connecticut
|
$1.95M
|
+$2.05M
|
+162,500
|
New
|
|
|
24
|
|
$1.89M
|
+$1.67M
|
+132,900
|
+552%
|
|
|
25
|
Acadian Asset Management
Boston,
Massachusetts
|
$1.89M
|
+$1.98M
|
+156,961
|
New
|
|
