|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$102M
|
+$673K
|
+35,876
|
+0.7%
|
|
|
2
|
|
$66.6M
|
+$483K
|
+25,753
|
+0.8%
|
|
|
3
|
Farallon Capital Management
San Francisco,
California
|
$53.8M
|
+$4.69M
|
+250,000
|
+10%
|
|
|
4
|
Adage Capital Partners
Boston,
Massachusetts
|
$49.3M
|
+$6.02M
|
+320,600
|
+15%
|
|
|
5
|
|
$48M
|
+$7.78M
|
+414,517
|
+20%
|
|
|
6
|
Johnson & Johnson Innovation - JJDC
New Brunswick,
New Jersey
|
$47.9M
|
–
|
–
|
–
|
|
|
7
|
BVF Inc
San Francisco,
California
|
$46.4M
|
+$93.8K
|
+5,000
|
+0.2%
|
|
|
8
|
Consonance Capital Management
New York
|
$46.3M
|
+$44.5M
|
+2,369,709
|
New
|
|
|
9
|
Baker Bros. Advisors
New York
|
$31.2M
|
-$5.92M
|
-315,248
|
-16%
|
|
|
10
|
Vanguard Group
Malvern,
Pennsylvania
|
$30.4M
|
+$2.48M
|
+132,098
|
+9%
|
|
|
11
|
Deerfield Management
New York
|
$23.1M
|
+$3.12M
|
+166,476
|
+16%
|
|
|
12
|
State Street
Boston,
Massachusetts
|
$22.6M
|
+$14.5M
|
+771,659
|
+202%
|
|
|
13
|
|
$15.9M
|
-$997K
|
-53,146
|
-6%
|
|
|
14
|
Novo Holdings A/S
Hellerup,
Denmark
|
$15.5M
|
-$559K
|
-29,800
|
-4%
|
|
|
15
|
Dimensional Fund Advisors
Austin,
Texas
|
$13.4M
|
-$30.8K
|
-1,641
|
-0.2%
|
|
|
16
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$11.5M
|
-$3.04M
|
-161,775
|
-22%
|
|
|
17
|
|
$10.3M
|
-$5.35M
|
-285,113
|
-35%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$8.58M
|
+$1.33M
|
+70,744
|
+19%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$7.52M
|
+$1.1M
|
+58,716
|
+18%
|
|
|
20
|
Sofinnova Investments
Menlo Park,
California
|
$6.99M
|
+$595K
|
+31,705
|
+10%
|
|
|
21
|
Two Sigma Advisers
New York
|
$6.94M
|
-$1.2M
|
-64,025
|
-15%
|
|
|
22
|
Renaissance Technologies
New York
|
$6.58M
|
-$3.67M
|
-195,600
|
-37%
|
|
|
23
|
|
$4.34M
|
-$5.78M
|
-307,968
|
-58%
|
|
|
24
|
Two Sigma Investments
New York
|
$4.3M
|
-$1.31M
|
-69,775
|
-24%
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
$4.23M
|
+$2.99M
|
+159,414
|
+279%
|
|
