RTW Investments’s Protagonist Therapeutics PTGX Stock Holding History

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$533M	Hold	5,059,053	–	–	5.31%	3
2025 Q4	$442M	Sell	5,059,053 -697,224	-12%	-$57.1M	4.43%	5
2025 Q3	$382M	Hold	5,756,277	–	–	4.71%	6
2025 Q2	$318M	Buy	5,756,277 +36,862	+0.6%	+$1.77M	4.53%	5
2025 Q1	$277M	Buy	5,719,415 +220,870	+4%	+$9.26M	4.23%	7
2024 Q4	$212M	Buy	5,498,545 +72,433	+1%	+$3.16M	3.21%	10
2024 Q3	$244M	Buy	5,426,112 +139,708	+3%	+$5.64M	3.53%	9
2024 Q2	$183M	Sell	5,286,404 -29,110	-0.5%	-$853K	2.84%	14
2024 Q1	$154M	Hold	5,315,514	–	–	2.27%	16
2023 Q4	$122M	Sell	5,315,514 -100,000	-2%	-$1.75M	1.9%	18
2023 Q3	$90.3M	Hold	5,415,514	–	–	1.91%	19
2023 Q2	$150M	Buy	5,415,514 +814,715	+18%	+$20.4M	2.85%	15
2023 Q1	$106M	Buy	4,600,799 +1,008,813	+28%	+$16.9M	2.2%	17
2022 Q4	$39.2M	Sell	3,591,986 -584,851	-14%	-$4.93M	0.8%	27
2022 Q3	$35.2M	Sell	4,176,837 -617,662	-13%	-$5.84M	0.81%	34
2022 Q2	$37.9M	Hold	4,794,499	–	–	0.98%	31
2022 Q1	$114M	Buy	4,794,499 +2,194,677	+84%	+$61.8M	2.35%	13
2021 Q4	$88.9M	Buy	2,599,822 +846,127	+48%	+$26.7M	1.3%	26
2021 Q3	$31.1M	Sell	1,753,695 -1,753,695	-50%	-$74.8M	0.47%	50
2021 Q2	$157M	Hold	3,507,390	–	–	2.38%	12
2021 Q1	$90.8M	Sell	3,507,390 -142,679	-4%	-$3.61M	1.42%	25
2020 Q4	$73.6M	Buy	3,650,069 +241,108	+7%	+$5.19M	1.23%	27
2020 Q3	$66.6M	Buy	3,408,961 +25,753	+0.8%	+$483K	1.6%	20
2020 Q2	$59.7M	Buy	3,383,208 +722,816	+27%	+$9.07M	1.68%	21
2020 Q1	$18.8M	Buy	2,660,392 +200,404	+8%	+$1.5M	0.81%	36
2019 Q4	$17.3M	Buy	2,459,988 +1,697,705	+223%	+$16.9M	0.65%	34
2019 Q3	$9.15M	Buy	+762,283	New	+$9.61M	0.54%	38