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Protagonist Therapeutics

274 hedge funds and large institutions have $3.15B invested in Protagonist Therapeutics in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 86 increasing their positions, 90 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
274
Holders Change
+34
Holders Change %
+14.17%
% of All Funds
3.72%
Holding in Top 10
14
Holding in Top 10 Change
+7
Holding in Top 10 Change %
+100%
% of All Funds
0.19%
New
72
Increased
86
Reduced
90
Closed
35
Calls
$51.1M
Puts
$31.9M
Net Calls
+$19.2M
Net Calls Change
+$20M
Name Holding Trade Value Shares
Change
Shares
Change %
BlackRock
1
BlackRock
New York
$471M -$7.15M -147,850 -1%
FCM
2
Farallon Capital Management
California
$295M +$8.56M +177,000 +3%
RI
3
RTW Investments
New York
$277M +$10.7M +220,870 +4%
Vanguard Group
4
Vanguard Group
Pennsylvania
$207M +$2.77M +57,181 +1%
DTC
5
Deep Track Capital
Connecticut
$145M +$96.7M +2,000,000 +200%
State Street
6
State Street
Massachusetts
$131M -$30.2M -624,442 -19%
BI
7
BVF Inc
California
$125M +$32.6M +675,000 +36%
JJ
8
Johnson & Johnson
New Jersey
$118M
Geode Capital Management
9
Geode Capital Management
Massachusetts
$68.9M +$2.25M +46,496 +3%
T. Rowe Price Associates
10
T. Rowe Price Associates
Maryland
$63.9M -$3.42M -70,646 -5%
PA
11
Perceptive Advisors
New York
$52.8M -$8.72M -180,391 -14%
Wellington Management Group
12
Wellington Management Group
Massachusetts
$47.7M +$2.29M +47,293 +5%
ACM
13
ADAR1 Capital Management
Texas
$45.4M -$3.9M -80,664 -8%
WP
14
Woodline Partners
California
$43.4M +$15.3M +315,372 +54%
Invesco
15
Invesco
Georgia
$41.6M +$5.84M +120,696 +16%
LCM
16
Lynx1 Capital Management
Puerto Rico
$35.4M +$35.4M +733,014 New
American Century Companies
17
American Century Companies
Missouri
$33.2M -$11.7M -242,462 -26%
Northern Trust
18
Northern Trust
Illinois
$30.9M +$528K +10,927 +2%
JFG
19
Jefferies Financial Group
New York
$30.6M -$41.5M -857,602 -58%
Charles Schwab
20
Charles Schwab
California
$27M -$1M -20,691 -4%
Goldman Sachs
21
Goldman Sachs
New York
$26.9M -$9.82M -203,139 -27%
EP
22
Eversept Partners
New York
$26.5M -$6.37M -131,671 -19%
6CM
23
683 Capital Management
New York
$24.2M +$4.35M +90,000 +22%
Morgan Stanley
24
Morgan Stanley
New York
$24M -$2.09M -43,210 -8%
Fidelity Investments
25
Fidelity Investments
Massachusetts
$23.1M +$1.73M +35,827 +8%