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Protagonist Therapeutics

140 hedge funds and large institutions have $1.19B invested in Protagonist Therapeutics in 2022 Q1 according to their latest regulatory filings, with 20 funds opening new positions, 54 increasing their positions, 47 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed

259% more call options, than puts

Call options by funds: $52.9M | Put options by funds: $14.7M

15% more repeat investments, than reductions

Existing positions increased: 54 | Existing positions reduced: 47

1% more ownership

Funds ownership: 103.59%104.59% (+1%)

6% less funds holding

Funds holding: 149140 (-9)

29% less capital invested

Capital invested by funds: $1.67B → $1.19B (-$486M)

31% less first-time investments, than exits

New positions opened: 20 | Existing positions closed: 29

50% less funds holding in top 10

Funds holding in top 10: 84 (-4)

Holders
140
Holders Change
-9
Holders Change %
-6.04%
% of All Funds
2.21%
Holding in Top 10
4
Holding in Top 10 Change
-4
Holding in Top 10 Change %
-50%
% of All Funds
0.06%
New
20
Increased
54
Reduced
47
Closed
29
Calls
$52.9M
Puts
$14.7M
Net Calls
+$38.2M
Net Calls Change
+$11.8M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$169M +$7.93M +281,302 +4%
RI
2
RTW Investments
New York
$114M +$61.8M +2,194,677 +84%
BI
3
BVF Inc
California
$99.1M +$15M +531,460 +15%
State Street
4
State Street
Massachusetts
$77.1M +$19.3M +685,238 +27%
BlackRock
5
BlackRock
New York
$76.9M -$999K -35,462 -1%
Point72 Asset Management
6
Point72 Asset Management
Connecticut
$69M +$14M +495,337 +20%
JJ
7
Johnson & Johnson
New Jersey
$58M
Vanguard Group
8
Vanguard Group
Pennsylvania
$55.2M -$510K -18,092 -0.8%
Morgan Stanley
9
Morgan Stanley
New York
$31.7M +$34.6M +1,229,687 +1,145%
FCM
10
Farallon Capital Management
California
$26.9M -$22.1M -782,677 -41%
Dimensional Fund Advisors
11
Dimensional Fund Advisors
Texas
$20.4M -$331K -11,759 -1%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$19.7M +$1.55M +54,840 +7%
Deutsche Bank
13
Deutsche Bank
Germany
$19.5M -$71.8K -2,549 -0.3%
OWP
14
Obermeyer Wealth Partners
Colorado
$19M +$357K +12,683 +2%
AG
15
Artal Group
Luxembourg
$18.9M -$12.7M -449,900 -36%
TLP
16
Tri Locum Partners
New York
$18.2M +$12.8M +455,321 +145%
CAC
17
Cowen and Company
New York
$17.1M +$20.3M +719,397 +22,637%
Adage Capital Partners
18
Adage Capital Partners
Massachusetts
$14.2M +$4.23M +150,000 +33%
WP
19
Woodline Partners
California
$13.9M +$2.7M +95,707 +19%
FFM
20
Fairmount Funds Management
Pennsylvania
$13M +$15.5M +549,988 New
SI
21
Sofinnova Investments
California
$13M +$1.84M +65,184 +14%
Millennium Management
22
Millennium Management
New York
$10.9M +$1.95M +69,042 +18%
Northern Trust
23
Northern Trust
Illinois
$10.3M -$573K -20,333 -4%
ACM
24
Altium Capital Management
New York
$9.14M +$1.13M +40,000 +12%
EC
25
EcoR1 Capital
California
$9.04M -$63.6M -2,257,995 -86%

PTGX Hedge Fund Activity: Q1 2022 in Review

140 of the 6,340 institutional investors tracked by Wall St. Rank reported a position in Protagonist Therapeutics (PTGX) for Q1 2022, worth a combined $1.19B — down 29% from $1.67B a quarter earlier.

Sellers outnumbered buyers: 29 funds closed out of PTGX and 20 opened new positions — a net loss of 9 holders — while 47 trimmed existing stakes and 54 added.

The largest buyer was RTW Investments, adding an estimated $61.8M. The largest seller was EcoR1 Capital, cutting an estimated $63.6M.

  • 140 institutional investors held Protagonist Therapeutics (PTGX) as of Q1 2022, down from 149 in Q4 2021.
  • Funds reported $1.19B of Protagonist Therapeutics stock for Q1 2022, down 29% quarter-over-quarter.
  • 20 funds opened new Protagonist Therapeutics positions in Q1 2022 and 29 closed out, a net change of -9 holders.
  • The largest Protagonist Therapeutics buyer in Q1 2022 was RTW Investments, an estimated $61.8M added.
  • The largest Protagonist Therapeutics seller in Q1 2022 was EcoR1 Capital, an estimated $63.6M sold.

Based on aggregated 13F filings for Q1 2022.