|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$24.4M
|
+$1.35M
|
+170,500
|
+5%
|
|
|
2
|
Farallon Capital Management
San Francisco,
California
|
$14.8M
|
-$345K
|
-43,528
|
-2%
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$11M
|
-$7.76M
|
-978,509
|
-37%
|
|
|
4
|
Great Point Partners
Greenwich,
Connecticut
|
$6.43M
|
-$213K
|
-26,831
|
-3%
|
|
|
5
|
Millennium Management
New York
|
$4.64M
|
-$2.73M
|
-343,647
|
-33%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$4.44M
|
+$1.03M
|
+129,285
|
+24%
|
|
|
7
|
Dimensional Fund Advisors
Austin,
Texas
|
$3.3M
|
+$970K
|
+122,250
|
+33%
|
|
|
8
|
VHCP Management III
New York
|
$2.85M
|
+$3.36M
|
+423,176
|
New
|
|
|
9
|
Renaissance Technologies
New York
|
$2.29M
|
-$1.57M
|
-197,400
|
-37%
|
|
|
10
|
|
$1.75M
|
+$168K
|
+21,126
|
+9%
|
|
|
11
|
Acadian Asset Management
Boston,
Massachusetts
|
$1.73M
|
+$51.7K
|
+6,516
|
+3%
|
|
|
12
|
VHCP Management II
New York
|
$1.68M
|
+$1.98M
|
+250,024
|
New
|
|
|
13
|
Tekla Capital Management
Boston,
Massachusetts
|
$1.33M
|
-$174K
|
-21,904
|
-10%
|
|
|
14
|
Wedge Capital Management
Charlotte,
North Carolina
|
$1.26M
|
–
|
–
|
–
|
|
|
15
|
|
$1.1M
|
-$612K
|
-77,114
|
-32%
|
|
|
16
|
Oxford Asset Management
Oxford,
United Kingdom
|
$947K
|
-$372K
|
-46,939
|
-25%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$792K
|
-$1.01K
|
-128
|
-0.1%
|
|
|
18
|
American Century Companies
Kansas City,
Missouri
|
$762K
|
-$277K
|
-34,921
|
-24%
|
|
|
19
|
Two Sigma Advisers
New York
|
$647K
|
-$372K
|
-46,900
|
-33%
|
|
|
20
|
Spark Investment Management
New York
|
$636K
|
-$351K
|
-44,200
|
-32%
|
|
|
21
|
Fosun International
Hong Kong,
China
|
$609K
|
+$766K
|
+96,513
|
New
|
|
|
22
|
Bridgeway Capital Management
Houston,
Texas
|
$576K
|
–
|
–
|
–
|
|
|
23
|
Barclays
London,
United Kingdom
|
$462K
|
+$544K
|
+68,602
|
New
|
|
|
24
|
Bank of New York Mellon
New York
|
$426K
|
–
|
–
|
–
|
|
|
25
|
Two Sigma Investments
New York
|
$385K
|
-$693K
|
-87,341
|
-60%
|
|
