|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$28.9M
|
+$98.7K
|
+13,177
|
+0.3%
|
|
|
2
|
|
$18.8M
|
+$1.5M
|
+200,404
|
+8%
|
|
|
3
|
Johnson & Johnson Innovation - JJDC
New Brunswick,
New Jersey
|
$17.3M
|
–
|
–
|
–
|
|
|
4
|
Baker Bros. Advisors
New York
|
$11.9M
|
+$3.78M
|
+504,882
|
+43%
|
|
|
5
|
|
$11M
|
-$33.7K
|
-4,501
|
-0.3%
|
|
|
6
|
Farallon Capital Management
San Francisco,
California
|
$10.6M
|
–
|
–
|
–
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$7M
|
+$12.6K
|
+1,684
|
+0.2%
|
|
|
8
|
|
$6.23M
|
+$4.68M
|
+624,546
|
+242%
|
|
|
9
|
Novo Holdings A/S
Hellerup,
Denmark
|
$4.93M
|
+$1.64M
|
+218,825
|
+46%
|
|
|
10
|
BVF Inc
San Francisco,
California
|
$4.89M
|
+$73.4K
|
+9,800
|
+1%
|
|
|
11
|
Dimensional Fund Advisors
Austin,
Texas
|
$4.76M
|
+$21.7K
|
+2,897
|
+0.4%
|
|
|
12
|
Renaissance Technologies
New York
|
$4.06M
|
-$320K
|
-42,724
|
-7%
|
|
|
13
|
Sphera Funds Management
Tel Aviv,
Israel
|
$3.71M
|
-$779K
|
-103,925
|
-16%
|
|
|
14
|
Citadel Advisors
Miami,
Florida
|
$3.31M
|
+$75.8K
|
+10,119
|
+2%
|
|
|
15
|
Millennium Management
New York
|
$2.42M
|
-$3.78M
|
-504,819
|
-60%
|
|
|
16
|
State Street
Boston,
Massachusetts
|
$2.24M
|
-$153K
|
-20,378
|
-6%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$2.07M
|
+$172K
|
+22,998
|
+8%
|
|
|
18
|
|
$1.98M
|
-$1.12M
|
-149,983
|
-35%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$1.81M
|
+$77.2K
|
+10,304
|
+4%
|
|
|
20
|
Ghost Tree Capital
New York
|
$1.61M
|
-$353K
|
-47,173
|
-17%
|
|
|
21
|
Two Sigma Advisers
New York
|
$1.59M
|
-$707K
|
-94,300
|
-30%
|
|
|
22
|
Ikarian Capital
Dallas,
Texas
|
$1.12M
|
+$599K
|
+79,896
|
+102%
|
|
|
23
|
|
$799K
|
+$848K
|
+113,140
|
New
|
|
|
24
|
Two Sigma Investments
New York
|
$774K
|
-$706K
|
-94,261
|
-46%
|
|
|
25
|
Russell Investments Group
London,
United Kingdom
|
$736K
|
+$426K
|
+56,872
|
+120%
|
|
