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Protagonist Therapeutics
PTGX

Name Holding Trade Value Shares
Change 		Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$45M +$29.1M +2,128,719 New
Adage Capital Partners
2
Adage Capital Partners
Massachusetts
$33.4M +$21.6M +1,581,076 New
CAM
3
Cormorant Asset Management
Massachusetts
$16.9M +$10.9M +800,000 New
RCM
4
RA Capital Management
Massachusetts
$15.9M +$10.3M +754,411 New
BI
5
BVF Inc
California
$7.92M +$5.13M +375,000 New
FCMI
6
Foresite Capital Management III
California
$6.29M +$4.73M +346,281 New
BFA
7
BlackRock Fund Advisors
California
$4.36M +$2.82M +206,455 New
Vanguard Group
8
Vanguard Group
Pennsylvania
$3.01M +$1.95M +142,468 New
DCM
9
DAFNA Capital Management
California
$2.62M +$1.69M +123,804 New
Geode Capital Management
10
Geode Capital Management
Massachusetts
$1.96M +$1.27M +92,820 New
BIT
11
BlackRock Institutional Trust
California
$1.4M +$906K +66,262 New
State Street
12
State Street
Massachusetts
$1.29M +$835K +61,121 New
SIM
13
Spark Investment Management
New York
$889K +$575K +42,100 New
GAMA
14
Graticule Asia Macro Advisors
New York
$673K +$435K +31,827 New
BIM
15
BlackRock Investment Management
Delaware
$611K +$395K +28,898 New
Northern Trust
16
Northern Trust
Illinois
$425K +$275K +20,137 New
CS
17
Credit Suisse
Switzerland
$358K +$231K +16,924 New
California State Teachers Retirement System (CalSTRS)
18
California State Teachers Retirement System (CalSTRS)
California
$340K +$220K +16,100 New
Bank of New York Mellon
19
Bank of New York Mellon
New York
$301K +$194K +14,202 New
Goldman Sachs
20
Goldman Sachs
New York
$282K +$182K +13,340 New
Jane Street
21
Jane Street
New York
$232K +$150K +10,964 New
TCIM
22
TIAA CREF Investment Management
New York
$213K +$138K +10,093 New
TA
23
Teachers Advisors
New York
$170K +$110K +8,037 New
BA
24
BlackRock Advisors
Delaware
$55K +$35.6K +2,605 New
SO
25
STRS Ohio
Ohio
$50K +$32.8K +2,400 New
1
2