|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$42.5M
|
-$1.08M
|
-97,845
|
-3%
|
|
|
2
|
Farallon Capital Management
San Francisco,
California
|
$18.2M
|
-$3.21M
|
-290,000
|
-16%
|
|
|
3
|
VHCP Management III
New York
|
$13M
|
+$2.91M
|
+263,025
|
+32%
|
|
|
4
|
BVF Inc
San Francisco,
California
|
$12.9M
|
-$657K
|
-59,453
|
-5%
|
|
|
5
|
|
$12.3M
|
+$8.22M
|
+743,632
|
+272%
|
|
|
6
|
Baker Bros. Advisors
New York
|
$12.1M
|
+$6.54M
|
+591,189
|
+146%
|
|
|
7
|
Millennium Management
New York
|
$9.82M
|
-$908K
|
-82,089
|
-9%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$9.69M
|
+$1.12M
|
+100,960
|
+14%
|
|
|
9
|
Dimensional Fund Advisors
Austin,
Texas
|
$9.01M
|
+$888K
|
+80,281
|
+12%
|
|
|
10
|
Acuta Capital Partners
Redwood City,
California
|
$8.13M
|
+$3.69M
|
+334,000
|
+99%
|
|
|
11
|
|
$6.69M
|
+$3.07M
|
+278,066
|
+99%
|
|
|
12
|
Renaissance Technologies
New York
|
$6.2M
|
+$1.19M
|
+107,300
|
+26%
|
|
|
13
|
VHCP Management II
New York
|
$5.17M
|
+$1.72M
|
+155,404
|
+57%
|
|
|
14
|
Citadel Advisors
Miami,
Florida
|
$4.96M
|
+$510K
|
+46,120
|
+13%
|
|
|
15
|
|
$4.81M
|
+$1.54M
|
+139,550
|
+54%
|
|
|
16
|
State Street
Boston,
Massachusetts
|
$3.18M
|
+$2.75M
|
+248,658
|
+1,770%
|
|
|
17
|
Oxford Asset Management
Oxford,
United Kingdom
|
$2.61M
|
+$816K
|
+73,811
|
+52%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$2.47M
|
+$787K
|
+71,207
|
+54%
|
|
|
19
|
Ghost Tree Capital
New York
|
$2.42M
|
-$5.53M
|
-500,000
|
-71%
|
|
|
20
|
Two Sigma Advisers
New York
|
$1.51M
|
+$345K
|
+31,200
|
+33%
|
|
|
21
|
Allianz Asset Management
Munich,
Germany
|
$1.5M
|
+$522K
|
+47,175
|
+61%
|
|
|
22
|
Two Sigma Investments
New York
|
$1.48M
|
+$843K
|
+76,247
|
+166%
|
|
|
23
|
Tekla Capital Management
Boston,
Massachusetts
|
$1.47M
|
-$620K
|
-56,084
|
-32%
|
|
|
24
|
Boothbay Fund Management
New York
|
$1.28M
|
+$1.17M
|
+105,965
|
New
|
|
|
25
|
UBS Group
Zurich,
Switzerland
|
$1.26M
|
+$1.13M
|
+102,556
|
+6,234%
|
|
