|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$170M
|
+$3M
|
+118,463
|
+2%
|
|
|
2
|
BVF Inc
San Francisco,
California
|
$103M
|
-$7.95M
|
-314,137
|
-7%
|
|
|
3
|
|
$90.8M
|
-$3.61M
|
-142,679
|
-4%
|
|
|
4
|
|
$77.7M
|
+$10.4M
|
+409,918
|
+16%
|
|
|
5
|
Consonance Capital Management
New York
|
$70.2M
|
-$506K
|
-20,000
|
-0.7%
|
|
|
6
|
Johnson & Johnson Innovation - JJDC
New Brunswick,
New Jersey
|
$63.4M
|
–
|
–
|
–
|
|
|
7
|
Farallon Capital Management
San Francisco,
California
|
$62.8M
|
–
|
–
|
–
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$55.4M
|
+$3.11M
|
+122,910
|
+6%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$44.4M
|
+$5.78M
|
+228,367
|
+15%
|
|
|
10
|
Baker Bros. Advisors
New York
|
$37.2M
|
–
|
–
|
–
|
|
|
11
|
Deerfield Management
New York
|
$32.6M
|
-$3.07M
|
-121,181
|
-9%
|
|
|
12
|
Point72 Asset Management
Stamford,
Connecticut
|
$24.4M
|
+$9.93M
|
+392,300
|
+71%
|
|
|
13
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$23.7M
|
+$1.73M
|
+68,195
|
+8%
|
|
|
14
|
Novo Holdings A/S
Hellerup,
Denmark
|
$22.5M
|
–
|
–
|
–
|
|
|
15
|
Dimensional Fund Advisors
Austin,
Texas
|
$17M
|
+$166K
|
+6,561
|
+1%
|
|
|
16
|
Sofinnova Investments
Menlo Park,
California
|
$17M
|
+$16.6M
|
+654,900
|
New
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$16.7M
|
+$3.48M
|
+137,378
|
+27%
|
|
|
18
|
Adage Capital Partners
Boston,
Massachusetts
|
$15.5M
|
-$13.9M
|
-550,000
|
-48%
|
|
|
19
|
|
$15.1M
|
-$2.99M
|
-118,110
|
-17%
|
|
|
20
|
Rothschild & Co Asset Management US
Stamford,
Connecticut
|
$11.2M
|
+$11M
|
+434,249
|
New
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$10.8M
|
+$299K
|
+11,796
|
+3%
|
|
|
22
|
|
$10.7M
|
-$3.48M
|
-137,653
|
-25%
|
|
|
23
|
Obermeyer Wealth Partners
Aspen,
Colorado
|
$10M
|
+$9.77M
|
+386,072
|
New
|
|
|
24
|
Commodore Capital
New York
|
$9.05M
|
+$53.1K
|
+2,100
|
+0.6%
|
|
|
25
|
Two Sigma Advisers
New York
|
$8.98M
|
-$521K
|
-20,600
|
-6%
|
|
