|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$91.2M
|
+$13.4M
|
+1,071,061
|
+26%
|
|
|
2
|
|
$59.7M
|
+$9.07M
|
+722,816
|
+27%
|
|
|
3
|
Farallon Capital Management
San Francisco,
California
|
$44.1M
|
+$12.5M
|
+1,000,000
|
+67%
|
|
|
4
|
Johnson & Johnson Innovation - JJDC
New Brunswick,
New Jersey
|
$43.3M
|
–
|
–
|
–
|
|
|
5
|
BVF Inc
San Francisco,
California
|
$41.8M
|
+$21M
|
+1,674,858
|
+242%
|
|
|
6
|
Adage Capital Partners
Boston,
Massachusetts
|
$38.9M
|
+$27.6M
|
+2,200,000
|
New
|
|
|
7
|
|
$36.1M
|
+$6.07M
|
+484,004
|
+31%
|
|
|
8
|
Baker Bros. Advisors
New York
|
$33.8M
|
+$2.91M
|
+232,282
|
+14%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$25.1M
|
+$5.38M
|
+428,892
|
+43%
|
|
|
10
|
Deerfield Management
New York
|
$17.9M
|
+$12.7M
|
+1,013,495
|
New
|
|
|
11
|
|
$14.8M
|
-$566K
|
-45,149
|
-5%
|
|
|
12
|
Novo Holdings A/S
Hellerup,
Denmark
|
$14.6M
|
+$1.58M
|
+126,270
|
+18%
|
|
|
13
|
|
$14.4M
|
+$6.68M
|
+532,412
|
+190%
|
|
|
14
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$13.2M
|
+$8.85M
|
+705,018
|
+1,654%
|
|
|
15
|
Dimensional Fund Advisors
Austin,
Texas
|
$12.1M
|
+$166K
|
+13,249
|
+2%
|
|
|
16
|
Renaissance Technologies
New York
|
$9.4M
|
-$541K
|
-43,100
|
-7%
|
|
|
17
|
|
$9.36M
|
+$5.85M
|
+466,347
|
+732%
|
|
|
18
|
Two Sigma Advisers
New York
|
$7.4M
|
+$2.44M
|
+194,500
|
+87%
|
|
|
19
|
Millennium Management
New York
|
$6.79M
|
+$527K
|
+42,030
|
+12%
|
|
|
20
|
State Street
Boston,
Massachusetts
|
$6.76M
|
+$817K
|
+65,102
|
+20%
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$6.5M
|
+$938K
|
+74,774
|
+25%
|
|
|
22
|
Sofinnova Investments
Menlo Park,
California
|
$5.76M
|
+$4.09M
|
+326,064
|
New
|
|
|
23
|
Northern Trust
Chicago,
Illinois
|
$5.75M
|
+$876K
|
+69,821
|
+27%
|
|
|
24
|
Two Sigma Investments
New York
|
$5.12M
|
+$2.26M
|
+180,355
|
+165%
|
|
|
25
|
|
$4.14M
|
+$1.87M
|
+149,351
|
+176%
|
|
