|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$45.3M
|
-$182K
|
-20,653
|
-0.6%
|
|
|
2
|
Farallon Capital Management
San Francisco,
California
|
$22.5M
|
-$3.62M
|
-409,674
|
-19%
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$14.1M
|
-$4.56M
|
-516,203
|
-31%
|
|
|
4
|
Millennium Management
New York
|
$11.2M
|
+$1.79M
|
+203,004
|
+29%
|
|
|
5
|
VHCP Management III
New York
|
$10.2M
|
+$3.41M
|
+386,147
|
+91%
|
|
|
6
|
Ghost Tree Capital
New York
|
$8.8M
|
+$6.18M
|
+700,000
|
New
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$8.79M
|
+$351K
|
+39,744
|
+6%
|
|
|
8
|
Dimensional Fund Advisors
Austin,
Texas
|
$8.34M
|
+$1.53M
|
+173,510
|
+35%
|
|
|
9
|
Renaissance Technologies
New York
|
$5.09M
|
+$575K
|
+65,200
|
+19%
|
|
|
10
|
Baker Bros. Advisors
New York
|
$5.08M
|
+$3.57M
|
+403,893
|
New
|
|
|
11
|
Citadel Advisors
Miami,
Florida
|
$4.57M
|
+$2.9M
|
+328,965
|
+946%
|
|
|
12
|
Acuta Capital Partners
Redwood City,
California
|
$4.24M
|
+$2.98M
|
+337,500
|
New
|
|
|
13
|
|
$3.53M
|
+$1.03M
|
+117,139
|
+72%
|
|
|
14
|
|
$3.44M
|
+$117K
|
+13,241
|
+5%
|
|
|
15
|
VHCP Management II
New York
|
$3.41M
|
+$188K
|
+21,353
|
+9%
|
|
|
16
|
|
$3.24M
|
+$2.1M
|
+238,083
|
+1,212%
|
|
|
17
|
Acadian Asset Management
Boston,
Massachusetts
|
$3.05M
|
-$118K
|
-13,358
|
-5%
|
|
|
18
|
Tekla Capital Management
Boston,
Massachusetts
|
$2.23M
|
-$174K
|
-19,713
|
-10%
|
|
|
19
|
Oxford Asset Management
Oxford,
United Kingdom
|
$1.78M
|
+$10.9K
|
+1,231
|
+0.9%
|
|
|
20
|
Wedge Capital Management
Charlotte,
North Carolina
|
$1.7M
|
-$461K
|
-52,257
|
-28%
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$1.67M
|
+$132K
|
+14,947
|
+13%
|
|
|
22
|
Bridgeway Capital Management
Houston,
Texas
|
$1.53M
|
+$316K
|
+35,800
|
+42%
|
|
|
23
|
|
$1.27M
|
+$644K
|
+72,993
|
+261%
|
|
|
24
|
Two Sigma Advisers
New York
|
$1.18M
|
-$21.2K
|
-2,400
|
-2%
|
|
|
25
|
Laurion Capital Management
New York
|
$1.08M
|
+$605K
|
+68,541
|
+401%
|
|
