Charles Schwab
SEPN

Charles Schwab’s Septerna Inc SEPN Stock Holding History

Charles Schwab’s Portfolio SEPN Stock Details SEPN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$6.26M Buy
187,041
+5,461
+3% +$155K ﹤0.01% 2371
2026
Q1 		$4.36M Sell
181,580
-5,661
-3% -$149K ﹤0.01% 2459
2025
Q4 		$5.22M Buy
187,241
+337
+0.2% +$8.05K ﹤0.01% 2433
2025
Q3 		$3.52M Buy
186,904
+32,123
+21% +$422K ﹤0.01% 2581
2025
Q2 		$1.64M Buy
154,781
+36,330
+31% +$299K ﹤0.01% 2734
2025
Q1 		$686K Sell
118,451
-21,165
-15% -$242K ﹤0.01% 2972
2024
Q4 		$3.2M Buy
+139,616
New +$3.3M ﹤0.01% 2532

Other funds holding SEPN

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
TGV
TRV GP V Boston, Massachusetts $498M AUM 267.53% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return
TGV
TRV GP VI Boston, Massachusetts $232M AUM 247.08% 1-Year Est. Return
SB
Samsara BioCapital Palo Alto, California $1.22B AUM 242.83% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
SL
Siren LLC Greenwich, Connecticut $4.94B AUM 244.43% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM

Charles Schwab's SEPN Position: Q2 2026 in Review

Charles Schwab increased its Septerna Inc (SEPN) stake by 3% in Q2 2026, buying an estimated $155K and bringing the position to 187,041 shares worth $6.26M. The position accounts for ﹤0.01% of the portfolio, ranked #2371.

Charles Schwab first reported a position in SEPN in Q4 2024 and has held it in 7 quarters since. 154 funds tracked by Wall St. Rank hold SEPN as of Q2 2026.

  • Charles Schwab held 187,041 shares of Septerna Inc worth $6.26M as of Q2 2026.
  • Charles Schwab bought 5,461 Septerna Inc shares in Q2 2026, an estimated $155K.
  • Septerna Inc made up ﹤0.01% of Charles Schwab's portfolio in Q2 2026, its #2371 holding.
  • Charles Schwab first reported a position in Septerna Inc in Q4 2024 and has held it in 7 quarters since.
  • 154 funds tracked by Wall St. Rank held Septerna Inc as of Q2 2026.

Based on Charles Schwab's 13F filing for Q2 2026, filed 14 Aug 2026.