BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
-2.68%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$17.3B
AUM Growth
+$17.3B
Cap. Flow
-$421M
Cap. Flow %
-2.43%
Top 10 Hldgs %
87.61%
Holding
112
New
6
Increased
20
Reduced
13
Closed
5

Top Buys

1
ROIV icon
Roivant Sciences
ROIV
$46.9M
2
ABCL icon
AbCellera Biologics
ABCL
$38.8M
3
KYMR icon
Kymera Therapeutics
KYMR
$34.4M
4
IMGN
Immunogen Inc
IMGN
$28.7M
5
ACAD icon
Acadia Pharmaceuticals
ACAD
$22.2M

Top Sells

1
SGEN
Seagen Inc. Common Stock
SGEN
$454M
2
KRYS icon
Krystal Biotech
KRYS
$15.6M
3
BPMC
Blueprint Medicines
BPMC
$15M
4
FGEN icon
FibroGen
FGEN
$6.48M
5
VSTM icon
Verastem
VSTM
$5.88M

Sector Composition

1 Healthcare 99.16%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
HOOK
76
DELISTED
HOOKIPA Pharma
HOOK
$3.89M 0.02%
4,425,535
+950,000
+27% +$836K
EWTX icon
77
Edgewise Therapeutics
EWTX
$1.54B
$3.88M 0.02%
500,000
– –
GRCL
78
DELISTED
Gracell Biotechnologies Inc. American Depositary Shares
GRCL
$3.81M 0.02%
+1,000,000
New +$3.81M
LPTX icon
79
Leap Therapeutics
LPTX
$12M
$3.67M 0.02%
1,172,175
-6,253,395
-84% +$1.34M
TLIS
80
DELISTED
Talis Biomedical Corporation Common Stock
TLIS
$3.66M 0.02%
7,624,835
– –
IPSC icon
81
Century Therapeutics
IPSC
$40.4M
$3.63M 0.02%
1,149,340
– –
MRSN icon
82
Mersana Therapeutics
MRSN
$34.8M
$3.57M 0.02%
1,086,115
-800,000
-42% -$2.63M
BCEL
83
DELISTED
Atreca, Inc. Class A Common Stock
BCEL
$3.46M 0.02%
3,532,760
– –
NGNE icon
84
Neurogene
NGNE
$284M
$3.17M 0.02%
3,821,740
– –
DSGN icon
85
Design Therapeutics
DSGN
$339M
$3.15M 0.02%
500,000
-126,884
-20% -$799K
XNCR icon
86
Xencor
XNCR
$594M
$3.07M 0.02%
123,127
– –
TIL icon
87
Instil Bio
TIL
$196M
$2.91M 0.02%
5,273,789
– –
TNGX icon
88
Tango Therapeutics
TNGX
$745M
$2.49M 0.01%
750,000
– –
PCVX icon
89
Vaxcyte
PCVX
$4.17B
$2.44M 0.01%
48,885
– –
ACHL
90
DELISTED
Achilles Therapeutics plc American Depositary Shares
ACHL
$2.42M 0.01%
2,557,149
-34,217
-1% -$32.3K
VERA icon
91
Vera Therapeutics
VERA
$1.47B
$2.35M 0.01%
146,464
-186,869
-56% -$3M
PRAX icon
92
Praxis Precision Medicines
PRAX
$980M
$2.16M 0.01%
1,879,915
– –
ALGS icon
93
Aligos Therapeutics
ALGS
$75.1M
$2.02M 0.01%
2,076,400
– –
PMVP icon
94
PMV Pharmaceuticals
PMVP
$82.1M
$2.02M 0.01%
322,024
– –
ITOS
95
DELISTED
iTeos Therapeutics
ITOS
$1.99M 0.01%
150,346
– –
VOR icon
96
Vor Biopharma
VOR
$253M
$1.96M 0.01%
633,848
– –
KALA icon
97
KALA BIO
KALA
$105M
$1.7M 0.01%
116,213
+39,400
+51% +$575K
CATX icon
98
Perspective Therapeutics
CATX
$251M
$1.55M 0.01%
+2,319,286
New +$1.55M
SYRE icon
99
Spyre Therapeutics
SYRE
$1.02B
$1.54M 0.01%
3,410,106
– –
FGEN icon
100
FibroGen
FGEN
$48.4M
$643K ﹤0.01%
238,084
-2,399,300
-91% -$6.48M
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