BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+25.41%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$16.7B
AUM Growth
+$16.7B
Cap. Flow
-$302M
Cap. Flow %
-1.81%
Top 10 Hldgs %
86.98%
Holding
128
New
13
Increased
17
Reduced
8
Closed
15

Top Buys

1
SWTX
SpringWorks Therapeutics
SWTX
$39.8M
2
PRME icon
Prime Medicine
PRME
$19.1M
3
REPL icon
Replimune Group
REPL
$18.6M
4
SPRY icon
ARS Pharmaceuticals
SPRY
$17.1M
5
DNLI icon
Denali Therapeutics
DNLI
$13.9M

Top Sells

1
GBT
Global Blood Therapeutics, Inc.
GBT
$254M
2
CCXI
ChemoCentryx, Inc.
CCXI
$92.6M
3
TVTX icon
Travere Therapeutics
TVTX
$43.6M
4
FMTX
Forma Therapeutics Holdings, Inc. Common Stock
FMTX
$37.6M
5
ALT icon
Altimmune
ALT
$18.4M

Sector Composition

1 Healthcare 99.74%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
RVMD icon
76
Revolution Medicines
RVMD
$7.43B
$5.29M 0.03%
222,222
– –
EWTX icon
77
Edgewise Therapeutics
EWTX
$1.54B
$4.47M 0.03%
500,000
– –
PRAX icon
78
Praxis Precision Medicines
PRAX
$980M
$4.36M 0.03%
+1,830,315
New +$4.36M
TCRX icon
79
TScan Therapeutics
TCRX
$106M
$4.32M 0.03%
2,784,792
– –
ARAV
80
DELISTED
Aravive, Inc. Common Stock
ARAV
$4.3M 0.03%
+3,261,224
New +$4.3M
CYT
81
DELISTED
Cyteir Therapeutics, Inc. Common Stock
CYT
$4.11M 0.02%
2,492,118
-151,522
-6% -$250K
NTRA icon
82
Natera
NTRA
$23B
$4.02M 0.02%
100,000
– –
TLIS
83
DELISTED
Talis Biomedical Corporation Common Stock
TLIS
$3.4M 0.02%
7,624,835
– –
TIL icon
84
Instil Bio
TIL
$196M
$3.32M 0.02%
5,273,789
+1,380,089
+35% +$869K
XNCR icon
85
Xencor
XNCR
$594M
$3.21M 0.02%
+123,127
New +$3.21M
ITOS
86
DELISTED
iTeos Therapeutics
ITOS
$2.94M 0.02%
150,346
– –
KALA icon
87
KALA BIO
KALA
$105M
$2.93M 0.02%
+76,813
New +$2.93M
BCEL
88
DELISTED
Atreca, Inc. Class A Common Stock
BCEL
$2.83M 0.02%
3,532,760
– –
HOOK
89
DELISTED
HOOKIPA Pharma
HOOK
$2.82M 0.02%
3,475,535
+1,075,054
+45% +$871K
PMVP icon
90
PMV Pharmaceuticals
PMVP
$82.1M
$2.8M 0.02%
322,024
– –
ATRA icon
91
Atara Biotherapeutics
ATRA
$88.7M
$2.44M 0.01%
744,186
– –
NKTX icon
92
Nkarta
NKTX
$149M
$2.4M 0.01%
400,000
– –
PCVX icon
93
Vaxcyte
PCVX
$4.17B
$2.34M 0.01%
+48,885
New +$2.34M
ACHL
94
DELISTED
Achilles Therapeutics plc American Depositary Shares
ACHL
$2.33M 0.01%
2,591,366
– –
FATE icon
95
Fate Therapeutics
FATE
$115M
$2.18M 0.01%
215,695
– –
ALGS icon
96
Aligos Therapeutics
ALGS
$75.1M
$1.98M 0.01%
2,076,400
– –
NGNE icon
97
Neurogene
NGNE
$284M
$1.95M 0.01%
3,821,740
– –
KRON
98
DELISTED
Kronos Bio
KRON
$1.94M 0.01%
1,198,151
-341,465
-22% -$553K
SYRE icon
99
Spyre Therapeutics
SYRE
$1.02B
$1.53M 0.01%
3,410,106
– –
TCRR
100
DELISTED
TCR2 Therapeutics Inc. Common Stock
TCRR
$752K ﹤0.01%
753,064
– –
2 3
4
5 6