BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+3.62%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$22.8B
AUM Growth
+$22.8B
Cap. Flow
-$610M
Cap. Flow %
-2.68%
Top 10 Hldgs %
81.57%
Holding
135
New
6
Increased
16
Reduced
10
Closed
15

Top Buys

1
VERV
Verve Therapeutics
VERV
$85.3M
2
LEGN icon
Legend Biotech
LEGN
$63.6M
3
APLS icon
Apellis Pharmaceuticals
APLS
$37.8M
4
HRTX icon
Heron Therapeutics
HRTX
$33.2M
5
JBIO
Jade Biosciences, Inc. Common Stock
JBIO
$32.6M

Top Sells

1
ALXN
Alexion Pharmaceuticals Inc
ALXN
$611M
2
NVTA
Invitae Corporation
NVTA
$186M
3
PTGX icon
Protagonist Therapeutics
PTGX
$44M
4
CCXI
ChemoCentryx, Inc.
CCXI
$33.7M
5
ALT icon
Altimmune
ALT
$16.6M

Sector Composition

1 Healthcare 97.75%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
ASMB icon
76
Assembly Biosciences
ASMB
$183M
$8.18M 0.04%
175,718
+47,266
+37% +$2.2M
KRTX
77
DELISTED
Karuna Therapeutics, Inc. Common Stock
KRTX
$7.98M 0.04%
69,966
– –
MREO
78
Mereo BioPharma
MREO
$275M
$7.8M 0.03%
2,459,399
-4,260,549
-63% -$13.5M
SPRY icon
79
ARS Pharmaceuticals
SPRY
$1.08B
$7.36M 0.03%
238,095
– –
BLUE
80
DELISTED
bluebird bio
BLUE
$7.26M 0.03%
17,523
– –
RVMD icon
81
Revolution Medicines
RVMD
$7.43B
$7.05M 0.03%
222,222
– –
DNLI icon
82
Denali Therapeutics
DNLI
$2.24B
$6.96M 0.03%
88,738
– –
CHMA
83
DELISTED
Chiasma, Inc. Common Stock
CHMA
$6.72M 0.03%
1,420,740
+678,607
+91% +$3.21M
HOOK
84
DELISTED
HOOKIPA Pharma
HOOK
$6.42M 0.03%
70,048
– –
BNR
85
Burning Rock Biotech
BNR
$85.6M
$6.16M 0.03%
20,913
– –
REPL icon
86
Replimune Group
REPL
$460M
$5.9M 0.03%
153,512
– –
NGM
87
DELISTED
NGM Biopharmaceuticals, Inc. Common Stock
NGM
$5.75M 0.03%
291,801
– –
CABA icon
88
Cabaletta Bio
CABA
$144M
$5.47M 0.02%
636,363
– –
MGNX icon
89
MacroGenics
MGNX
$121M
$5.39M 0.02%
200,679
– –
ORTX
90
DELISTED
Orchard Therapeutics plc American Depositary Shares
ORTX
$5.23M 0.02%
119,200
+45,757
+62% +$2.01M
ALEC icon
91
Alector
ALEC
$282M
$4.98M 0.02%
239,228
– –
NEXI
92
DELISTED
NexImmune, Inc. Common Stock
NEXI
$4.8M 0.02%
11,765
– –
BMEA icon
93
Biomea Fusion
BMEA
$114M
$4.59M 0.02%
+294,117
New +$4.59M
GMDA
94
DELISTED
Gamida Cell Ltd. Ordinary Shares
GMDA
$3.91M 0.02%
610,626
-426,600
-41% -$2.73M
ITOS
95
DELISTED
iTeos Therapeutics
ITOS
$3.86M 0.02%
150,346
– –
HRMY icon
96
Harmony Biosciences
HRMY
$2.16B
$3.49M 0.02%
123,600
– –
TCDA
97
DELISTED
Tricida, Inc. Common Stock
TCDA
$3.15M 0.01%
729,300
– –
EVFM
98
DELISTED
Evofem Biosciences, Inc. Common Stock
EVFM
$3.05M 0.01%
179,807
– –
AKRO icon
99
Akero Therapeutics
AKRO
$3.65B
$2.94M 0.01%
118,378
– –
TCRR
100
DELISTED
TCR2 Therapeutics Inc. Common Stock
TCRR
$2.9M 0.01%
176,461
– –
2 3
4
5 6