BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+17.29%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$11B
AUM Growth
+$11B
Cap. Flow
-$1.16B
Cap. Flow %
-10.49%
Top 10 Hldgs %
83.4%
Holding
143
New
7
Increased
14
Reduced
16
Closed
6

Top Buys

1
AMRN
Amarin Corp
AMRN
$63.3M
2
SGEN
Seagen Inc. Common Stock
SGEN
$46.5M
3
ACAD icon
Acadia Pharmaceuticals
ACAD
$41.4M
4
NGNE icon
Neurogene
NGNE
$37.2M
5
EXEL icon
Exelixis
EXEL
$30M

Top Sells

1
XNPT
XENOPORT, INC.
XNPT
$24.5M
2
MDVN
MEDIVATION, INC.
MDVN
$19.9M
3
BCRX icon
BioCryst Pharmaceuticals
BCRX
$17.8M
4
NVAX icon
Novavax
NVAX
$17.3M
5
INSM icon
Insmed
INSM
$16M

Sector Composition

1 Healthcare 82.76%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
NVIV
76
DELISTED
InVivo Therapeutics Holdings Corp
NVIV
$2.72M 0.02%
21
– –
ECYT
77
DELISTED
Endocyte, Inc. Common Stock
ECYT
$2.69M 0.02%
868,983
-261,594
-23% -$808K
SYRE icon
78
Spyre Therapeutics
SYRE
$1.02B
$2.59M 0.02%
16,169
– –
RNAC icon
79
Cartesian Therapeutics
RNAC
$267M
$2.55M 0.02%
5,965
– –
OSIR
80
DELISTED
Osiris Therapeutics, Inc. Common Stock
OSIR
$2.48M 0.02%
499,193
– –
NBRV
81
DELISTED
Nabriva Therapeutics plc Ordinary Shares Ireland
NBRV
$2.47M 0.02%
1,400
– –
JUNO
82
DELISTED
Juno Therapeutics, Inc.
JUNO
$2.4M 0.02%
80,000
– –
EPZM
83
DELISTED
Epizyme, Inc
EPZM
$2.29M 0.02%
232,481
– –
KPTI icon
84
Karyopharm Therapeutics
KPTI
$61.4M
$2.11M 0.02%
14,466
– –
IONS icon
85
Ionis Pharmaceuticals
IONS
$9.64B
$2.09M 0.02%
57,140
– –
ENTA icon
86
Enanta Pharmaceuticals
ENTA
$189M
$2.01M 0.02%
75,357
– –
SCYX icon
87
SCYNEXIS
SCYX
$35.2M
$1.81M 0.02%
46,760
– –
ASMB icon
88
Assembly Biosciences
ASMB
$185M
$1.8M 0.02%
20,833
– –
QURE icon
89
uniQure
QURE
$954M
$1.76M 0.02%
230,000
– –
MDWD icon
90
MediWound
MDWD
$180M
$1.74M 0.02%
32,286
– –
ISEE
91
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$1.64M 0.01%
35,649
– –
MYOK
92
DELISTED
MyoKardia, Inc. Common Stock
MYOK
$1.63M 0.01%
+100,000
New +$1.63M
MCRB icon
93
Seres Therapeutics
MCRB
$162M
$1.54M 0.01%
6,250
– –
PTN
94
DELISTED
Palatin Technologies
PTN
$1.29M 0.01%
82,000
– –
CLLS
95
Cellectis
CLLS
$260M
$1.2M 0.01%
50,000
– –
CLCD
96
DELISTED
CoLucid Pharmaceuticals, Inc.
CLCD
$1.16M 0.01%
+30,310
New +$1.16M
FLGT icon
97
Fulgent Genetics
FLGT
$674M
$1.15M 0.01%
+125,000
New +$1.15M
IMDZ
98
DELISTED
Immune Design Corp.
IMDZ
$1.13M 0.01%
148,937
– –
AFMD
99
DELISTED
Affimed
AFMD
$1.11M 0.01%
40,000
– –
ALDX icon
100
Aldeyra Therapeutics
ALDX
$350M
$1.11M 0.01%
142,000
– –
2 3
4
5 6