BBA
Baker Bros. Advisors Portfolio holdings
AUM
$10.3B
This Quarter Return
+23.73%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$8.79B
AUM Growth
+$8.79B
(-49%)
Cap. Flow
-$9.7B
Cap. Flow
% of AUM
-110.42%
Top 10 Holdings %
Top 10 Hldgs %
80.97%
Holding
105
New
4
Increased
23
Reduced
13
Closed
21
Top Buys
| 1 |
MRTX
Mirati Therapeutics, Inc. Common Stock
MRTX
|
$159M |
| 2 |
Madrigal Pharmaceuticals
MDGL
|
$98.3M |
| 3 |
Revolution Medicines
RVMD
|
$70.5M |
| 4 |
CERE
Cerevel Therapeutics Holdings, Inc. Common Stock
CERE
|
$67.8M |
| 5 |
Replimune Group
REPL
|
$41.9M |
Top Sells
| 1 |
SGEN
Seagen Inc. Common Stock
SGEN
|
$9.45B |
| 2 |
BioMarin Pharmaceuticals
BMRN
|
$337M |
| 3 |
ONC
BeOne Medicines Ltd. American Depositary Shares
ONC
|
$198M |
| 4 |
SWTX
SpringWorks Therapeutics
SWTX
|
$69.4M |
| 5 |
Roivant Sciences
ROIV
|
$48.1M |
Sector Composition
| 1 | Healthcare | 98.42% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Shares Change % | Capital Flow | |
|---|---|---|---|---|---|---|
51
Sana Biotechnology
SANA
$759M
| $8.16M | 0.09% |
2,000,000
| – | – |
|
52
Sagimet Biosciences
SGMT
$239M
| $7.89M | 0.09% |
1,456,518
+641,159
| +79% | +$3.48M |
|
53
Celcuity
CELC
$2.3B
| $7.8M | 0.09% |
535,478
| – | – |
|
54
Athira Pharma
ATHA
$15.5M
| $7.66M | 0.09% |
3,153,807
| – | – |
|
|
OPT
55
DELISTED
Opthea Limited American Depositary Shares
OPT
| $7.64M | 0.09% |
2,588,645
-102,246
| -4% | -$302K |
|
56
Tango Therapeutics
TNGX
$745M
| $7.43M | 0.08% |
750,000
| – | – |
|
57
Taysha Gene Therapies
TSHA
$791M
| $7.09M | 0.08% |
4,004,756
+1,500,000
| +60% | +$2.66M |
|
|
HOOK
58
DELISTED
HOOKIPA Pharma
HOOK
| $6.58M | 0.07% |
8,128,151
+62,753
| +0.8% | +$50.8K |
|
59
Mirum Pharmaceuticals
MIRM
$3.75B
| $5.62M | 0.06% |
190,476
| – | – |
|
60
Xencor
XNCR
$594M
| $5.21M | 0.06% |
245,431
+122,304
| +99% | +$2.6M |
|
61
Leap Therapeutics
LPTX
$12M
| $4.86M | 0.06% |
1,172,175
| – | – |
|
62
Design Therapeutics
DSGN
$339M
| $3.98M | 0.05% |
1,500,000
| – | – |
|
|
TLIS
63
DELISTED
Talis Biomedical Corporation Common Stock
TLIS
| $3.79M | 0.04% |
508,323
| – | – |
|
64
Perspective Therapeutics
CATX
$251M
| $3.07M | 0.03% |
7,639,703
| – | – |
|
65
Vaxcyte
PCVX
$4.17B
| $3.07M | 0.03% |
48,885
| – | – |
|
66
Praxis Precision Medicines
PRAX
$980M
| $2.93M | 0.03% |
131,533
-1,748,382
| -93% | +$138K |
|
67
Century Therapeutics
IPSC
$40.4M
| $2.65M | 0.03% |
797,460
-351,880
| -31% | -$1.17M |
|
68
Mersana Therapeutics
MRSN
$34.8M
| $2.52M | 0.03% |
1,086,115
| – | – |
|
69
Compass Therapeutics
CMPX
$466M
| $2.43M | 0.03% |
1,557,630
| – | – |
|
|
ACHL
70
DELISTED
Achilles Therapeutics plc American Depositary Shares
ACHL
| $1.87M | 0.02% |
2,102,792
-454,357
| -18% | -$404K |
|
71
KALA BIO
KALA
$105M
| $1.87M | 0.02% |
266,613
| – | – |
|
72
Aligos Therapeutics
ALGS
$75.1M
| $1.38M | 0.02% |
2,076,400
| – | – |
|
|
NVTA
73
DELISTED
Invitae Corporation
NVTA
| $1.11M | 0.01% |
1,764,546
| – | – |
|
74
Pfizer
PFE
$141B
| $1.01M | 0.01% |
+35,000
| New | +$1.01M |
|
75
PMV Pharmaceuticals
PMVP
$82.1M
| $998K | 0.01% |
322,024
| – | – |
|