BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
-6.2%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$20.6B
AUM Growth
+$20.6B
Cap. Flow
+$247M
Cap. Flow %
1.2%
Top 10 Hldgs %
83.49%
Holding
127
New
5
Increased
17
Reduced
7
Closed
5

Top Buys

1
INCY icon
Incyte
INCY
$117M
2
TRDA icon
Entrada Therapeutics
TRDA
$80.5M
3
CCXI
ChemoCentryx, Inc.
CCXI
$48.4M
4
TSVT
2seventy bio
TSVT
$21.4M
5
TVTX icon
Travere Therapeutics
TVTX
$19.5M

Top Sells

1
SGEN
Seagen Inc. Common Stock
SGEN
$61.1M
2
FLGT icon
Fulgent Genetics
FLGT
$20.1M
3
BLUE
bluebird bio
BLUE
$13.6M
4
MIRM icon
Mirum Pharmaceuticals
MIRM
$12.9M
5
AUPH icon
Aurinia Pharmaceuticals
AUPH
$11.5M

Sector Composition

1 Healthcare 98.2%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
XENE icon
51
Xenon Pharmaceuticals
XENE
$2.99B
$23.5M 0.11%
751,639
– –
DBVT
52
DBV Technologies
DBVT
$249M
$23.4M 0.11%
14,614,264
– –
AXSM icon
53
Axsome Therapeutics
AXSM
$6.09B
$23.1M 0.11%
610,970
+71,913
+13% +$2.72M
JBIO
54
Jade Biosciences, Inc. Common Stock
JBIO
$245M
$21.6M 0.11%
1,831,789
+179,618
+11% +$2.12M
TSVT
55
DELISTED
2seventy bio
TSVT
$21.4M 0.1%
+833,236
New +$21.4M
FLGT icon
56
Fulgent Genetics
FLGT
$674M
$20.3M 0.1%
201,444
-199,572
-50% -$20.1M
NGNE icon
57
Neurogene
NGNE
$284M
$18.4M 0.09%
3,821,740
– –
OTIC
58
DELISTED
Otonomy, Inc.
OTIC
$16.3M 0.08%
7,844,692
+150,654
+2% +$313K
SYRE icon
59
Spyre Therapeutics
SYRE
$1.02B
$16.2M 0.08%
3,410,106
– –
BCAB icon
60
BioAtla
BCAB
$28.7M
$16.2M 0.08%
825,000
– –
SRZN icon
61
Surrozen
SRZN
$107M
$16.1M 0.08%
2,500,000
– –
REPL icon
62
Replimune Group
REPL
$460M
$16.1M 0.08%
593,395
+439,883
+287% +$11.9M
DICE
63
DELISTED
DICE Therapeutics, Inc. Common Stock
DICE
$14.9M 0.07%
588,235
– –
ANAB icon
64
AnaptysBio
ANAB
$630M
$14.8M 0.07%
427,179
– –
AFMD
65
DELISTED
Affimed
AFMD
$14.6M 0.07%
2,653,169
+2,488,564
+1,512% +$13.7M
ACHL
66
DELISTED
Achilles Therapeutics plc American Depositary Shares
ACHL
$13M 0.06%
2,591,366
– –
CNTA
67
Centessa Pharmaceuticals
CNTA
$2.13B
$12.7M 0.06%
1,127,273
– –
TCDA
68
DELISTED
Tricida, Inc. Common Stock
TCDA
$12.3M 0.06%
1,285,014
+247,582
+24% +$2.37M
RLMD icon
69
Relmada Therapeutics
RLMD
$48.8M
$11.2M 0.05%
495,113
+294,117
+146% +$6.63M
SRPT icon
70
Sarepta Therapeutics
SRPT
$1.98B
$11.1M 0.05%
+123,456
New +$11.1M
BCEL
71
DELISTED
Atreca, Inc. Class A Common Stock
BCEL
$10.7M 0.05%
3,532,760
– –
ATHA icon
72
Athira Pharma
ATHA
$15.5M
$10.5M 0.05%
806,367
– –
ALT icon
73
Altimmune
ALT
$325M
$9.82M 0.05%
1,072,038
– –
CYT
74
DELISTED
Cyteir Therapeutics, Inc. Common Stock
CYT
$9.24M 0.05%
812,640
– –
KRTX
75
DELISTED
Karuna Therapeutics, Inc. Common Stock
KRTX
$9.17M 0.04%
69,966
– –
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3
4 5