BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+0.82%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$22.8B
AUM Growth
+$22.8B
Cap. Flow
+$265M
Cap. Flow %
1.16%
Top 10 Hldgs %
82.65%
Holding
132
New
12
Increased
20
Reduced
6
Closed
10

Top Buys

1
ASND icon
Ascendis Pharma
ASND
$160M
2
PACB icon
Pacific Biosciences
PACB
$57.3M
3
KOD icon
Kodiak Sciences
KOD
$52.2M
4
TVTX icon
Travere Therapeutics
TVTX
$44.9M
5
BLUE
bluebird bio
BLUE
$43.4M

Top Sells

1
APLS icon
Apellis Pharmaceuticals
APLS
$144M
2
ADCT icon
ADC Therapeutics
ADCT
$34.5M
3
AMRN
Amarin Corp
AMRN
$23.4M
4
PTGX icon
Protagonist Therapeutics
PTGX
$20.4M
5
AUPH icon
Aurinia Pharmaceuticals
AUPH
$13.3M

Sector Composition

1 Healthcare 97.89%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
OPT
51
DELISTED
Opthea Limited American Depositary Shares
OPT
$27.1M 0.12%
3,382,797
-29,265
-0.9% -$234K
BCAB icon
52
BioAtla
BCAB
$28.7M
$24.3M 0.11%
825,000
– –
KDNY
53
DELISTED
Chinook Therapeutics, Inc. Common Stock
KDNY
$24.3M 0.11%
1,903,069
+822,676
+76% +$10.5M
NVAX icon
54
Novavax
NVAX
$1.2B
$22.5M 0.1%
108,756
-35,000
-24% -$7.26M
RETA
55
DELISTED
Reata Pharmaceuticals, Inc. Class A Common Stock
RETA
$22.5M 0.1%
223,976
– –
BCEL
56
DELISTED
Atreca, Inc. Class A Common Stock
BCEL
$22M 0.1%
3,532,760
– –
DSGN icon
57
Design Therapeutics
DSGN
$339M
$21.1M 0.09%
1,436,636
– –
ACHL
58
DELISTED
Achilles Therapeutics plc American Depositary Shares
ACHL
$20.2M 0.09%
2,591,366
– –
CRNX icon
59
Crinetics Pharmaceuticals
CRNX
$3.26B
$19.4M 0.09%
920,656
– –
DICE
60
DELISTED
DICE Therapeutics, Inc. Common Stock
DICE
$19.3M 0.08%
+588,235
New +$19.3M
CNTA
61
Centessa Pharmaceuticals
CNTA
$2.13B
$18.8M 0.08%
1,127,273
+727,273
+182% +$12.1M
AXSM icon
62
Axsome Therapeutics
AXSM
$6.09B
$17.8M 0.08%
539,057
– –
SRZN icon
63
Surrozen
SRZN
$107M
$17.7M 0.08%
+2,500,000
New +$17.7M
OTIC
64
DELISTED
Otonomy, Inc.
OTIC
$14.8M 0.06%
7,694,038
+471,564
+7% +$905K
CYT
65
DELISTED
Cyteir Therapeutics, Inc. Common Stock
CYT
$14.3M 0.06%
812,640
– –
MIRM icon
66
Mirum Pharmaceuticals
MIRM
$3.75B
$12.9M 0.06%
647,313
– –
ALBO
67
DELISTED
Albireo Pharma, Inc. Common Stock
ALBO
$12.9M 0.06%
412,466
– –
ALT icon
68
Altimmune
ALT
$325M
$12.1M 0.05%
1,072,038
– –
TCRX icon
69
TScan Therapeutics
TCRX
$106M
$11.9M 0.05%
+1,425,000
New +$11.9M
ANAB icon
70
AnaptysBio
ANAB
$630M
$11.6M 0.05%
427,179
– –
AUPH icon
71
Aurinia Pharmaceuticals
AUPH
$1.58B
$11.5M 0.05%
520,523
-599,439
-54% -$13.3M
XENE icon
72
Xenon Pharmaceuticals
XENE
$2.99B
$11.5M 0.05%
751,639
– –
TNGX icon
73
Tango Therapeutics
TNGX
$745M
$9.7M 0.04%
+750,000
New +$9.7M
MGNX icon
74
MacroGenics
MGNX
$121M
$9.27M 0.04%
442,579
+241,900
+121% +$5.07M
KRTX
75
DELISTED
Karuna Therapeutics, Inc. Common Stock
KRTX
$8.56M 0.04%
69,966
– –
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3
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