BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+17.29%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$11B
AUM Growth
+$11B
Cap. Flow
+$82.4M
Cap. Flow %
0.75%
Top 10 Hldgs %
83.4%
Holding
143
New
7
Increased
14
Reduced
17
Closed
6

Top Buys

1
AMRN
Amarin Corp
AMRN
$63.3M
2
SGEN
Seagen Inc. Common Stock
SGEN
$46.5M
3
ACAD icon
Acadia Pharmaceuticals
ACAD
$41.4M
4
NGNE icon
Neurogene
NGNE
$37.2M
5
EXEL icon
Exelixis
EXEL
$30M

Top Sells

1
XNPT
XENOPORT, INC.
XNPT
$24.5M
2
MDVN
MEDIVATION, INC.
MDVN
$19.9M
3
BCRX icon
BioCryst Pharmaceuticals
BCRX
$17.8M
4
NVAX icon
Novavax
NVAX
$17.3M
5
INSM icon
Insmed
INSM
$16M

Sector Composition

1 Healthcare 82.76%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
ITCI
51
DELISTED
Intra-Cellular Therapies Inc.
ITCI
$9.28M 0.08%
609,166
– –
IMGN
52
DELISTED
Immunogen Inc
IMGN
$8.08M 0.07%
3,015,353
– –
LGND icon
53
Ligand Pharmaceuticals
LGND
$3.25B
$7.49M 0.07%
73,386
– –
ALDR
54
DELISTED
Alder Biopharmaceuticals, Inc.
ALDR
$7.12M 0.06%
217,328
– –
RARE icon
55
Ultragenyx Pharmaceutical
RARE
$3.04B
$7.09M 0.06%
100,000
-10,894
-10% -$773K
TRIL
56
DELISTED
Trillium Therapeutics Inc.
TRIL
$6.12M 0.06%
413,697
+201,905
+95% +$2.99M
INSM icon
57
Insmed
INSM
$30.3B
$5.81M 0.05%
400,000
-1,100,000
-73% -$16M
ARCT icon
58
Arcturus Therapeutics
ARCT
$467M
$5.77M 0.05%
2,336,359
– –
PRQR icon
59
ProQR Therapeutics
PRQR
$256M
$5.74M 0.05%
860,464
-373,631
-30% -$2.49M
NDRM
60
DELISTED
NeuroDerm Ltd. Ordinary Shares
NDRM
$5.64M 0.05%
305,000
– –
CPRX icon
61
Catalyst Pharmaceutical
CPRX
$2.42B
$5.56M 0.05%
5,102,153
-20,000
-0.4% -$21.8K
NTRA icon
62
Natera
NTRA
$23B
$5M 0.05%
450,000
– –
GNMX
63
DELISTED
Aevi Genomic Medicine, Inc.
GNMX
$4.91M 0.04%
880,539
– –
AKTX
64
Akari Therapeutics
AKTX
$21.4M
$4.23M 0.04%
496,901
– –
NERV icon
65
Minerva Neurosciences
NERV
$16.8M
$3.65M 0.03%
258,805
-249,600
-49% -$3.52M
STML
66
DELISTED
Stemline Therapeutics, Inc.
STML
$3.61M 0.03%
333,497
– –
LOXO
67
DELISTED
Loxo Oncology, Inc
LOXO
$3.61M 0.03%
137,735
– –
RXDX
68
DELISTED
Ignyta, Inc.
RXDX
$3.59M 0.03%
571,000
– –
VIRX
69
DELISTED
Viracta Therapeutics, Inc. Common Stock
VIRX
$3.24M 0.03%
741,665
-3,708,335
-83% –
CNCE
70
DELISTED
Concert Pharmaceuticals, Inc.
CNCE
$3.21M 0.03%
316,976
-153,082
-33% -$1.55M
TRVN
71
DELISTED
Trevena, Inc.
TRVN
$3.04M 0.03%
450,000
– –
SYRS
72
DELISTED
Syros Pharmaceuticals, Inc. Common Stock
SYRS
$2.84M 0.03%
204,465
– –
ADMS
73
DELISTED
Adamas Pharmaceuticals, Inc.
ADMS
$2.83M 0.03%
172,630
– –
TARA icon
74
Protara Therapeutics
TARA
$125M
$2.79M 0.03%
298,591
– –
CBIO
75
Crescent Biopharma, Inc. Common Stock
CBIO
$184M
$2.73M 0.02%
381,235
– –
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3
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