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Rhythm Pharmaceuticals
RYTM

Name Holding Trade Value Shares
Change 		Change in
Stake
PCH
26
Polar Capital Holdings
United Kingdom
$26.5M -$55.5M -1,000,000 -67%
OM
27
Opaleye Management
Massachusetts
$26M -$555K -10,000 -2%
SI
28
Sofinnova Investments
California
$23.7M +$2.74M +49,411 +12%
Charles Schwab
29
Charles Schwab
California
$23.6M +$287K +5,179 +1%
Voloridge Investment Management
30
Voloridge Investment Management
Florida
$22.4M +$2.35M +42,331 +11%
O
31
OrbiMed
New York
$20.1M -$1.11M -20,000 -5%
Balyasny Asset Management
32
Balyasny Asset Management
Illinois
$18.8M +$12.1M +217,349 +157%
SCM
33
Silverarc Capital Management
Massachusetts
$17.9M +$3.53M +63,709 +23%
Franklin Resources
34
Franklin Resources
California
$17.3M +$3.22M +57,955 +22%
CS
35
Candriam SCA
Luxembourg
$15.4M -$2.27M -40,923 -12%
SL
36
Siren LLC
Connecticut
$14.7M +$15.4M +277,533 New
UBS Group
37
UBS Group
Switzerland
$14.4M +$990K +17,844 +7%
Invesco
38
Invesco
Georgia
$13.9M -$2.27M -40,944 -14%
Pictet Asset Management
39
Pictet Asset Management
Switzerland
$13.9M -$6.44M -116,003 -31%
Comerica Bank
40
Comerica Bank
Texas
$13M +$12.6M +227,641 +1,330%
Norges Bank
41
Norges Bank
Norway
$11.8M +$989K +17,835 +9%
Millennium Management
42
Millennium Management
New York
$11.5M +$11.2M +202,120 +1,325%
Qube Research & Technologies (QRT)
43
Qube Research & Technologies (QRT)
United Kingdom
$11.5M +$6.71M +120,958 +127%
CSS
44
Cubist Systematic Strategies
Connecticut
$9.21M +$9.64M +173,822 New
CAM
45
Cormorant Asset Management
Massachusetts
$7.95M -$13.9M -250,000 -63%
Nuveen
46
Nuveen
North Carolina
$7.8M +$22.1K +398 +0.3%
Bank of New York Mellon
47
Bank of New York Mellon
New York
$7.76M -$92.2K -1,661 -1%
JP Morgan Chase
48
JP Morgan Chase
New York
$7.61M -$6.71M -120,945 -46%
PAM
49
Panagora Asset Management
Massachusetts
$7.48M +$7.83M +141,162 New
SB
50
Samsara BioCapital
California
$7.32M -$1.92M -34,529 -20%
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