|
1
|
Primecap Management
Pasadena,
California
|
$172M
|
+$12.3M
|
+662,798
|
+10%
|
|
|
2
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$155M
|
+$35.5M
|
+1,911,266
|
+43%
|
|
|
3
|
Baker Bros. Advisors
New York
|
$149M
|
+$36M
|
+1,937,640
|
+47%
|
|
|
4
|
RA Capital Management
Boston,
Massachusetts
|
$134M
|
+$11.2M
|
+600,000
|
+12%
|
|
|
5
|
|
$117M
|
+$30.1M
|
+1,616,792
|
+51%
|
|
|
6
|
NEA Management Company
Timonium,
Maryland
|
$108M
|
–
|
–
|
–
|
|
|
7
|
|
$86.7M
|
+$43.9M
|
+2,359,924
|
+200%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$76.6M
|
+$53.5M
|
+2,876,846
|
+1,146%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$54.7M
|
+$1.57M
|
+84,546
|
+4%
|
|
|
10
|
Frazier Life Sciences Management
Palo Alto,
California
|
$46.4M
|
+$35.2M
|
+1,894,000
|
New
|
|
|
11
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$43.1M
|
+$6.65M
|
+357,567
|
+25%
|
|
|
12
|
Alkeon Capital Management
New York
|
$41.8M
|
+$3.81M
|
+205,000
|
+14%
|
|
|
13
|
Janus Henderson Group
London,
|
$38.2M
|
-$9.65M
|
-518,994
|
-25%
|
|
|
14
|
Fidelity Investments
Boston,
Massachusetts
|
$33.6M
|
+$15.1M
|
+813,954
|
+146%
|
|
|
15
|
Opaleye Management
Boston,
Massachusetts
|
$19.8M
|
+$8.33M
|
+448,000
|
+124%
|
|
|
16
|
Polar Capital Holdings
London,
United Kingdom
|
$17.5M
|
+$13.3M
|
+714,739
|
New
|
|
|
17
|
Assenagon Asset Management
Senningerberg,
Luxembourg
|
$11.5M
|
-$4.08M
|
-219,310
|
-32%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$9.51M
|
-$217K
|
-11,682
|
-3%
|
|
|
19
|
Samsara BioCapital
Palo Alto,
California
|
$8.46M
|
–
|
–
|
–
|
|
|
20
|
|
$6.67M
|
+$5.02M
|
+269,921
|
+11,912%
|
|
|
21
|
Rafferty Asset Management
New York
|
$6.43M
|
+$4.88M
|
+262,288
|
New
|
|
|
22
|
Voloridge Investment Management
Jupiter,
Florida
|
$5.96M
|
+$4.53M
|
+243,408
|
New
|
|
|
23
|
|
$5.64M
|
-$3.73M
|
-200,550
|
-47%
|
|
|
24
|
Dimensional Fund Advisors
Austin,
Texas
|
$5.47M
|
-$560K
|
-30,110
|
-12%
|
|
|
25
|
Bank of America
Charlotte,
North Carolina
|
$5.35M
|
+$3.15M
|
+169,297
|
+345%
|
|
