|
1
|
Primecap Management
Pasadena,
California
|
$300M
|
-$17.4M
|
-435,200
|
-6%
|
|
|
2
|
|
$277M
|
+$8.47M
|
+212,277
|
+3%
|
|
|
3
|
Baker Bros. Advisors
New York
|
$263M
|
–
|
–
|
–
|
|
|
4
|
RA Capital Management
Boston,
Massachusetts
|
$250M
|
+$30.1M
|
+754,000
|
+14%
|
|
|
5
|
|
$217M
|
+$7.07M
|
+177,034
|
+3%
|
|
|
6
|
Perceptive Advisors
New York
|
$142M
|
+$7.11M
|
+178,000
|
+5%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$138M
|
+$2.26M
|
+56,549
|
+2%
|
|
|
8
|
NEA Management Company
Timonium,
Maryland
|
$119M
|
–
|
–
|
–
|
|
|
9
|
Frazier Life Sciences Management
Palo Alto,
California
|
$97.4M
|
+$7.23M
|
+181,125
|
+8%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$82.3M
|
-$40.3M
|
-1,009,956
|
-34%
|
|
|
11
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$68.2M
|
-$12.5K
|
-313
|
-0%
|
|
|
12
|
Polar Capital Holdings
London,
United Kingdom
|
$61.6M
|
–
|
–
|
–
|
|
|
13
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$52.6M
|
-$9.68M
|
-242,400
|
-16%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$51.4M
|
+$2.87M
|
+71,984
|
+6%
|
|
|
15
|
Commodore Capital
New York
|
$50.3M
|
+$6.99M
|
+175,000
|
+17%
|
|
|
16
|
Driehaus Capital Management
Chicago,
Illinois
|
$48.5M
|
+$13M
|
+326,865
|
+38%
|
|
|
17
|
Alkeon Capital Management
New York
|
$41.1M
|
+$39.9M
|
+1,000,000
|
New
|
|
|
18
|
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Toronto,
Ontario, Canada
|
$39.7M
|
+$9.44M
|
+236,600
|
+32%
|
|
|
19
|
Checkpoint Capital
San Francisco,
California
|
$37.9M
|
+$3.86M
|
+96,600
|
+12%
|
|
|
20
|
Pictet Asset Management
Carouge,
Switzerland
|
$32.9M
|
-$16.4M
|
-409,883
|
-34%
|
|
|
21
|
|
$28.9M
|
–
|
–
|
–
|
|
|
22
|
Janus Henderson Group
London,
|
$24.4M
|
-$1.11M
|
-27,785
|
-4%
|
|
|
23
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$21.6M
|
+$1.77M
|
+44,409
|
+9%
|
|
|
24
|
Opaleye Management
Boston,
Massachusetts
|
$21.1M
|
–
|
–
|
–
|
|
|
25
|
Northern Trust
Chicago,
Illinois
|
$20.5M
|
-$136K
|
-3,407
|
-0.7%
|
|
