|
1
|
Primecap Management
Pasadena,
California
|
$201M
|
-$2.97M
|
-115,750
|
-2%
|
|
|
2
|
Baker Bros. Advisors
New York
|
$185M
|
+$7.5M
|
+291,906
|
+5%
|
|
|
3
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$184M
|
-$61.3K
|
-2,384
|
-0%
|
|
|
4
|
RA Capital Management
Boston,
Massachusetts
|
$161M
|
+$1.16M
|
+45,000
|
+0.8%
|
|
|
5
|
|
$151M
|
+$10.9M
|
+424,614
|
+9%
|
|
|
6
|
NEA Management Company
Timonium,
Maryland
|
$143M
|
-$60.4K
|
-2,350
|
-0%
|
|
|
7
|
|
$108M
|
+$4.79M
|
+186,215
|
+5%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$92.6M
|
+$1.36M
|
+52,793
|
+2%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$75.6M
|
+$9.3M
|
+362,042
|
+16%
|
|
|
10
|
Alkeon Capital Management
New York
|
$65.2M
|
+$13.7M
|
+533,262
|
+31%
|
|
|
11
|
Frazier Life Sciences Management
Palo Alto,
California
|
$55.2M
|
–
|
–
|
–
|
|
|
12
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$51.3M
|
–
|
–
|
–
|
|
|
13
|
Polar Capital Holdings
London,
United Kingdom
|
$36.4M
|
+$13.8M
|
+535,261
|
+75%
|
|
|
14
|
Janus Henderson Group
London,
|
$36.1M
|
-$8.25M
|
-320,930
|
-21%
|
|
|
15
|
Fidelity Investments
Boston,
Massachusetts
|
$22.5M
|
-$15.4M
|
-597,920
|
-44%
|
|
|
16
|
Opaleye Management
Boston,
Massachusetts
|
$21.4M
|
-$1.93M
|
-75,000
|
-9%
|
|
|
17
|
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
$20.2M
|
+$12.3M
|
+479,520
|
+224%
|
|
|
18
|
Assenagon Asset Management
Senningerberg,
Luxembourg
|
$13.5M
|
-$177K
|
-6,894
|
-1%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$13.4M
|
+$1.81M
|
+70,398
|
+18%
|
|
|
20
|
|
$10.4M
|
+$4.43M
|
+172,461
|
+94%
|
|
|
21
|
Samsara BioCapital
Palo Alto,
California
|
$10.1M
|
–
|
–
|
–
|
|
|
22
|
|
$9.73M
|
+$8.59M
|
+334,273
|
New
|
|
|
23
|
Rafferty Asset Management
New York
|
$8.91M
|
+$1.12M
|
+43,725
|
+17%
|
|
|
24
|
|
$8.02M
|
+$86.7K
|
+3,374
|
+1%
|
|
|
25
|
Bank of America
Charlotte,
North Carolina
|
$7.75M
|
+$1.23M
|
+47,744
|
+22%
|
|
