|
1
|
|
$389M
|
+$3.39M
|
+61,457
|
+0.9%
|
|
|
2
|
Primecap Management
Pasadena,
California
|
$368M
|
-$35.7M
|
-645,721
|
-9%
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$341M
|
–
|
–
|
–
|
|
|
4
|
Baker Bros. Advisors
New York
|
$341M
|
-$17.4M
|
-314,117
|
-5%
|
|
|
5
|
Perceptive Advisors
New York
|
$206M
|
+$6.64M
|
+120,259
|
+3%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$193M
|
-$293K
|
-5,311
|
-0.2%
|
|
|
7
|
NEA Management Company
Timonium,
Maryland
|
$163M
|
–
|
–
|
–
|
|
|
8
|
Frazier Life Sciences Management
Palo Alto,
California
|
$105M
|
-$30.2M
|
-547,144
|
-23%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$103M
|
-$8.41M
|
-152,296
|
-8%
|
|
|
10
|
|
$101M
|
-$114M
|
-2,067,590
|
-53%
|
|
|
11
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$86.7M
|
-$6.31M
|
-114,265
|
-7%
|
|
|
12
|
Polar Capital Holdings
London,
United Kingdom
|
$84M
|
–
|
–
|
–
|
|
|
13
|
Driehaus Capital Management
Chicago,
Illinois
|
$72.3M
|
-$470K
|
-8,515
|
-0.7%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$70.3M
|
-$21.5K
|
-389
|
-0%
|
|
|
15
|
Janus Henderson Group
London,
|
$68.3M
|
+$34.3M
|
+621,432
|
+104%
|
|
|
16
|
Alkeon Capital Management
New York
|
$65.4M
|
–
|
–
|
–
|
|
|
17
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$65.1M
|
-$3.61M
|
-65,375
|
-5%
|
|
|
18
|
Checkpoint Capital
San Francisco,
California
|
$40.8M
|
+$3.57M
|
+64,601
|
+10%
|
|
|
19
|
Marshall Wace
London,
United Kingdom
|
$38.8M
|
+$15.8M
|
+286,188
|
+70%
|
|
|
20
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$38.4M
|
+$7.44M
|
+134,622
|
+24%
|
|
|
21
|
Hood River Capital Management
Palm Beach Gardens,
Florida
|
$36M
|
+$1.61M
|
+29,093
|
+5%
|
|
|
22
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$34.6M
|
-$1M
|
-18,143
|
-3%
|
|
|
23
|
|
$31.4M
|
+$5.27M
|
+95,483
|
+21%
|
|
|
24
|
Northern Trust
Chicago,
Illinois
|
$30.5M
|
+$2.59M
|
+46,848
|
+9%
|
|
|
25
|
Opaleye Management
Boston,
Massachusetts
|
$28M
|
–
|
–
|
–
|
|
