|
1
|
RA Capital Management
Boston,
Massachusetts
|
$580M
|
–
|
–
|
–
|
|
|
2
|
|
$542M
|
-$5.85M
|
-60,183
|
-1%
|
|
|
3
|
Baker Bros. Advisors
New York
|
$487M
|
–
|
–
|
–
|
|
|
4
|
Primecap Management
Pasadena,
California
|
$297M
|
-$5.95M
|
-61,160
|
-2%
|
|
|
5
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$264M
|
+$296M
|
+3,040,718
|
New
|
|
|
6
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$258M
|
+$289M
|
+2,967,825
|
New
|
|
|
7
|
Perceptive Advisors
New York
|
$206M
|
-$16.8M
|
-172,596
|
-7%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$198M
|
+$7.12M
|
+73,236
|
+3%
|
|
|
9
|
|
$171M
|
+$13.1M
|
+134,566
|
+7%
|
|
|
10
|
Westfield Capital Management
Boston,
Massachusetts
|
$168M
|
+$64.4M
|
+661,965
|
+52%
|
|
|
11
|
Fidelity Investments
Boston,
Massachusetts
|
$147M
|
-$1.62M
|
-16,646
|
-1%
|
|
|
12
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$144M
|
+$9.14M
|
+94,029
|
+6%
|
|
|
13
|
Polar Capital Holdings
London,
United Kingdom
|
$141M
|
+$41.8M
|
+430,194
|
+36%
|
|
|
14
|
Citadel Advisors
Miami,
Florida
|
$123M
|
+$123M
|
+1,265,297
|
+825%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$123M
|
+$3.94M
|
+40,540
|
+3%
|
|
|
16
|
|
$120M
|
+$12.6M
|
+129,655
|
+9%
|
|
|
17
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$112M
|
-$32.8M
|
-337,538
|
-21%
|
|
|
18
|
Checkpoint Capital
San Francisco,
California
|
$107M
|
+$22.9M
|
+235,000
|
+24%
|
|
|
19
|
AllianceBernstein
Nashville,
Tennessee
|
$97.5M
|
-$1.93M
|
-19,820
|
-2%
|
|
|
20
|
Capital Research Global Investors
Los Angeles,
California
|
$97M
|
+$12.7M
|
+130,374
|
+13%
|
|
|
21
|
Janus Henderson Group
London,
|
$79.9M
|
-$20.2M
|
-207,972
|
-18%
|
|
|
22
|
Point72 Asset Management
Stamford,
Connecticut
|
$73.6M
|
+$40.6M
|
+417,381
|
+97%
|
|
|
23
|
Woodline Partners
San Francisco,
California
|
$66M
|
+$6.82M
|
+70,112
|
+10%
|
|
|
24
|
Adage Capital Partners
Boston,
Massachusetts
|
$63.1M
|
+$10.1M
|
+104,159
|
+17%
|
|
|
25
|
Siren LLC
Greenwich,
Connecticut
|
$63.1M
|
+$21.9M
|
+225,536
|
+45%
|
|
