|
1
|
Primecap Management
Pasadena,
California
|
$378M
|
-$4.58M
|
-95,480
|
-1%
|
|
|
2
|
|
$361M
|
+$7.06M
|
+147,335
|
+2%
|
|
|
3
|
Baker Bros. Advisors
New York
|
$335M
|
+$48
|
+1
|
+0%
|
|
|
4
|
RA Capital Management
Boston,
Massachusetts
|
$319M
|
–
|
–
|
–
|
|
|
5
|
|
$203M
|
-$67.5M
|
-1,408,839
|
-27%
|
|
|
6
|
Perceptive Advisors
New York
|
$187M
|
+$5.44M
|
+113,635
|
+3%
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$181M
|
+$4.18M
|
+87,216
|
+3%
|
|
|
8
|
NEA Management Company
Timonium,
Maryland
|
$152M
|
–
|
–
|
–
|
|
|
9
|
Frazier Life Sciences Management
Palo Alto,
California
|
$127M
|
+$2.19M
|
+45,648
|
+2%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$104M
|
-$513K
|
-10,716
|
-0.5%
|
|
|
11
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$87.2M
|
+$149K
|
+3,116
|
+0.2%
|
|
|
12
|
Polar Capital Holdings
London,
United Kingdom
|
$78.6M
|
–
|
–
|
–
|
|
|
13
|
Driehaus Capital Management
Chicago,
Illinois
|
$68.1M
|
+$5.61M
|
+117,120
|
+10%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$65.8M
|
+$168K
|
+3,499
|
+0.3%
|
|
|
15
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$64.3M
|
-$2.51M
|
-52,400
|
-4%
|
|
|
16
|
Alkeon Capital Management
New York
|
$61.2M
|
+$8.04M
|
+167,700
|
+17%
|
|
|
17
|
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Toronto,
Ontario, Canada
|
$58.2M
|
+$6.89M
|
+143,800
|
+15%
|
|
|
18
|
Checkpoint Capital
San Francisco,
California
|
$34.8M
|
-$12.4M
|
-258,719
|
-28%
|
|
|
19
|
Commodore Capital
New York
|
$34.1M
|
-$27.6M
|
-575,000
|
-47%
|
|
|
20
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$33.4M
|
+$30.5M
|
+636,628
|
New
|
|
|
21
|
Hood River Capital Management
Palm Beach Gardens,
Florida
|
$32.2M
|
+$29.4M
|
+614,598
|
New
|
|
|
22
|
Janus Henderson Group
London,
|
$31.3M
|
+$215K
|
+4,480
|
+0.8%
|
|
|
23
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$28.8M
|
+$1.18M
|
+24,588
|
+5%
|
|
|
24
|
Opaleye Management
Boston,
Massachusetts
|
$26.2M
|
-$719K
|
-15,000
|
-3%
|
|
|
25
|
Northern Trust
Chicago,
Illinois
|
$26.1M
|
-$47.1K
|
-982
|
-0.2%
|
|
